Fluorescein hydrazide 

Fluorescein hydrazide is a sensitive fluorescent probe for Hg²⁺ and Co²⁺ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM^[1][2][3].

Fluorescein hydrazide 与 Hg²⁺ 形成络合物，引发 Fluorescein hydrazide 分子结构的变化，引起其吸收光谱和荧光光谱的变化，从而改变 Fluorescein hydrazide 溶液的颜色和荧光强度^[2]。
Fluorescein hydrazide 可用于检测水、食品和生物样品中的汞污染，在环境监测、食品安全和生物医药等领域具有广泛的应用。^[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

346.34

C₂₀H₁₄N₂O₄

78044-20-9

固体

White to off-white

523

488

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

• [1]. Yusha Feng, et al. A novel "turn-on" thiooxofluorescein-based colorimetric and fluorescent sensor for Hg2+ and its application in living cells. Talanta. 2017 Aug 1;170:103-110.  [Content Brief]

  [2]. Xie Z, et al. Sensitive colorimetric and fluorescent detection of mercury using fluorescein derivations[J]. 2012.

  [3]. Mori I, et al., Selective and sensitive fluorometric determinations of cobalt(II) and hydrogen peroxide with fluorescein-hydrazide. Talanta. 1998 Nov;47(3):631-7.  [Content Brief]