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  2. TENM1 - teneurin transmembrane protein 1 Gene

TENM1 - teneurin transmembrane protein 1 Gene

中文名称:teneurin 跨膜蛋白 1

种属: Homo sapiens

同用名: TNM; ODZ1; ODZ3; TEN1; TNM1; ten-1; TEN-M1

基因 ID: 10178 | 基因类型: protein coding

关于 TENM1

Cytogenetic location: Xq25 Genomic coordinates (GRCh38): X:124,375,903-125,204,312 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues, 4 paralogues and is associated with 1 phenotype. Broad expression in prostate (RPKM 2.1), brain (RPKM 2.0) and 17 other tissues.

功能概要

该基因编码的蛋白质属于生腱蛋白家族和 teneurin 亚家族。它在神经元中表达,可作为细胞信号转导器发挥作用。已经为该基因发现了几种编码不同亚型的可变剪接转录物变体。[RefSeq 提供,2009 年 9 月]

The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

TENM1 基因产物(3)

mRNA Protein Name
NM_001163278.2 NP_001156750.1 teneurin-1 isoform 1 precursor
NM_001163279.1 NP_001156751.1 teneurin-1 isoform 2 precursor
NM_014253.3 NP_055068.2 teneurin-1 isoform 3 precursor

TENM1 蛋白结构

Ten_N

Ten_N: Teneurin Intracellular Region (17 - 168)

Ten_N

Ten_N: Teneurin Intracellular Region (179 - 317)

hEGF

hEGF: Human growth factor-like EGF (740 - 752)

Tox-GHH

Tox-GHH: GHH signature containing HNH/Endo VII superfamily nuclease toxin (2640 - 2718)

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  • 2725 a.a.
蛋白主名 其他名称

teneurin-1

odz (odd Oz/ten-m, Drosophila) homolog 3

关联疾病

疾病名称 别名
Anosmia, Isolated Congenital

ANIC

Isolated Congenital Anosmia

Anosmia, Congenital

Congenital Anosmia

Anal Margin Carcinoma

Carcinoma Of Anal Margin

Perianal Skin Carcinoma

Anal Canal Carcinoma

Anal Canal Cancer

Anal Canal And Perianal Gland Carcinoma

Carcinoma Of The Anal Canal

Carcinoma Of Anal Canal

Microphthalmia

Microphthalmos

Isolated Anophthalmia-Microphthalmia Syndrome

Isolated Microphthalmia-Anophthalmia-Coloboma

Simple Microphthalmos

Clinical Anophthalmia

Isolated Anophthalmia - Microphthalmia

Isolated Pure Microphthalmia

Mac Spectrum

Microphthalmia-Anophthalmia-Coloboma Spectrum

Primitive Anophthalmia

Globe Of Eye Small

Small Eyeball

Hypoplasia Of Eye

Isolated Nanophthalmos

Rudimentary Eye

Dysplasia Of Eye

Cerebral Palsy

Infantile Cerebral Palsy

Mixed Cerebral Palsy

Palsy Cerebral

Palsy, Cerebral

Cerebral Palsy, Mixed

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TENM1 VGNC VGNC:47246
Mus musculus TENM1 MGD MGI:1345185
Felis catus TENM1 VGNC VGNC:68620
Rattus norvegicus TENM1 RGD RGD:1561678
Macaca mulatta TENM1 VGNC VGNC:79969
Bos taurus TENM1 VGNC VGNC:35741