2. Gene
  3. Fig4 - FIG4 phosphoinositide 5-phosphatase Gene

Fig4 - FIG4 phosphoinositide 5-phosphatase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sac3; A530089I17Rik

基因 ID: 103199 | 基因类型: protein coding

关于 Fig4

功能概要

Predicted to enable phosphatidylinositol bisphosphate Phosphatase activity; phosphatidylinositol-3-phosphatase activity; and phosphatidylinositol-4-phosphate Phosphatase activity. Acts upstream of or within several processes, including negative regulation of myelination; nervous system development; and phosphatidylinositol metabolic process. Predicted to be located in endosome membrane and lipid droplet. Predicted to colocalize with Golgi apparatus; endoplasmic reticulum; and recycling endosome. Is expressed in cerebral cortex; ganglia; nucleus pulposus; thymus primordium; and vibrissa. Used to study Charcot-Marie-Tooth disease type 4J and Yunis-Varon syndrome. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4J; Yunis-Varon syndrome; amyotrophic lateral sclerosis type 11; and bilateral parasagittal parieto-occipital polymicrogyria. Orthologous to human FIG4 (FIG4 phosphoinositide 5-phosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Fig4 基因产物(1)

mRNA Protein Name
NM_133999.1 NP_598760.1 polyphosphoinositide phosphatase
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
17572665 MGI
acts upstream of or within myelin assembly IGI
IGI: 通过遗传相互作用推断
22028665 MGI
acts upstream of myelination IGI
IGI: 通过遗传相互作用推断
22028665 MGI
acts upstream of myelination IMP
IMP: 通过突变表型推断
22028665 MGI
acts upstream of or within negative regulation of myelination IGI
IGI: 通过遗传相互作用推断
22028665 MGI
acts upstream of or within negative regulation of myelination IMP
IMP: 通过突变表型推断
22028665 MGI
acts upstream of or within neuron development IGI
IGI: 通过遗传相互作用推断
22028665 MGI
acts upstream of or within neuron development IMP
IMP: 通过突变表型推断
17572665 MGI
acts upstream of or within phosphatidylinositol metabolic process IMP
IMP: 通过突变表型推断
17572665 MGI
acts upstream of or within pigmentation IMP
IMP: 通过突变表型推断
17572665 MGI
acts upstream of or within vacuole organization IMP
IMP: 通过突变表型推断
17572665 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

polyphosphoinositide phosphatase

FIG4 homolog

SAC domain-containing protein 3

Sac domain-containing inositol phosphatase 3

phosphatidylinositol 3,5-bisphosphate 5-phosphatase

serine-protein phosphatase FIG4

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04944 FIG4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22170 Fig4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fig4 NCBI NCBI:9896
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