2. Gene
  3. IVNS1ABP - influenza virus NS1A binding protein Gene

IVNS1ABP - influenza virus NS1A binding protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：流感病毒 NS1A 结合蛋白

种属: Homo sapiens

同用名: ND1; ARA3; NS-1; IMD70; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068

基因 ID: 10625 | 基因类型: protein coding

关于 IVNS1ABP

Cytogenetic location: 1q25.3 Genomic coordinates (GRCh38): 1:185,296,388-185,317,243 (from NCBI)

This gene has 9 transcripts (splice variants), 223 orthologues, 54 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 56.1), kidney (RPKM 31.5) and 24 other tissues.

功能概要

参与 RNA 剪接；蛋白质泛素化的负调控；和对病毒的反应。位于胞质溶胶中。与免疫缺陷有关 70。[由基因组资源联盟提供，2022 年 4 月]

Involved in RNA splicing; negative regulation of protein ubiquitination; and response to virus. Located in cytosol. Implicated in immunodeficiency 70. [provided by Alliance of Genome Resources, Apr 2022]

IVNS1ABP 基因产物(1)

mRNA Protein Name
NM_006469.5 NP_006460.2 influenza virus NS1A-binding protein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23825951 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in RNA splicing IMP
IMP: 通过突变表型推断
23825951 GOA
involved in negative regulation of protein ubiquitination IMP
IMP: 通过突变表型推断
25619834 GOA
involved in response to virus IMP
IMP: 通过突变表型推断
23825951 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IVNS1ABP 蛋白结构

BTB

BTB: BTB/POZ domain (22 - 126)

BACK

BACK: BTB And C-terminal Kelch (134 - 221)

Kelch_1

Kelch_1: Kelch motif (357 - 402)

Kelch_1

Kelch_1: Kelch motif (404 - 449)

Kelch_1

Kelch_1: Kelch motif (453 - 499)

Kelch_1

Kelch_1: Kelch motif (501 - 546)

Kelch_1

Kelch_1: Kelch motif (548 - 592)

Kelch_1

Kelch_1: Kelch motif (595 - 635)

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  • 642 a.a.
蛋白主名 其他名称

influenza virus NS1A-binding protein

NCX downstream gene 1

关联疾病

疾病名称 别名
Immunodeficiency 70

IMD70
Influenza

Flu

Influenza With Non-Respiratory Manifestation

Influenza With Other Manifestations

Influenza, Human

Influenza, Susceptibility To

Seasonal Influenza, Virus Identified
Leber Hereditary Optic Neuropathy, Modifier Of

Leber Optic Atrophy

Leber Hereditary Optic Neuropathy

LHON

Leber'S Hereditary Optic Neuropathy

Leber Optic Atrophy, Susceptibility To

Leber'S Optic Atrophy

LOAM

Loas

Leber'S Disease

Leber'S Optic Neuropathy

Optic Atrophy, Hereditary, Leber

Lhon, Modifier Of

Optic Atrophy, Leber Type

Hereditary Optic Neuroretinopathy

Leber Hereditary Optic Atrophy

Loa

Optic Atrophy Leber Type

Leber Hereditary Optic Neuropathy, Modifier

Leber Hereditary Optic Neuropathy Susceptibility

Modifier Of Leber Hereditary Optic Neuropathy

Lebers Hereditary Optic Neuropathy

Leber Congenital Amaurosis
Tick-Borne Encephalitis

Siberian Tick-Borne Encephalitis

Encephalitis, Tick-Borne

Central European Encephalitis

Far Eastern Tbe

Russian Spring-Summer Encephalitis

Taiga Encephalitis

West-Siberian Encephalitis

Western European Tick-Borne Encephalitis

Tbe

Encephalitis Tick-Borne

Encephalitis, Central European

Encephalitis, Far Eastern Russian
Japanese Encephalitis

Japanese B Encephalitis

Je

Encephalitis Japanese

Encephalitis, Japanese

Russian Autumnal Encephalitis

Je - [Japanese Encephalitis]

Japanese Encephalitis Virus Disease

Jbe - [Japanese B Encephalitis}

B Type Encephalitis
Dengue Disease

Dengue Fever

Dengue

Df

Dengue Shock Syndrome

Dengue Virus Infection

Breakbone Fever

Classic Dengue

Classical Dengue

Dengue Hemorrhagic Fever

Hemorrhagic Dengue

Philippine Hemorrhagic Fever

Singapore Hemorrhagic Fever

Thai Hemorrhagic Fever

Severe Dengue

Dengue Fever Without Warning Signs

Dengue Haemorrhagic Fever Grade 1

Dengue Haemorrhagic Fever Without Warning Signs

Bangkok Haemorrhagic Fever

Singapore Haemorrhagic Fever

Thailand Haemorrhagic Fever

Southeast Asia Haemorrhagic Fever

Dhf -[Dengue Haemorrhagic Fever]

Dengue Fever With Warning Signs

Dengue Haemorrhagic Fever With Warning Signs

Dengue Haemorrhagic Fever Grade 2

Philippine Haemorrhagic Fever
Newcastle Disease

Newcastle'S Disease

Pseudo-Fowlpest
Dengue Hemorrhagic Fever

Severe Dengue

Dengue Haemorrhagic Fever

Dhf

Severe Dengue Haemorrhagic Fever

Severe Dengue Fever

Dengue Shock Syndrome
Retinal Vasculitis
Dengue Shock Syndrome

Dss
Shrimp Allergy
Venezuelan Hemorrhagic Fever

Guanarito Hemorrhagic Fever

Vehf - [Venezuelan Haemorrhagic Fever]
Viral Infectious Disease

Viral Disease

Arbovirus Infections

Virus Infection

Virus Diseases

Viral Infection

Viral Infections

Virus Infections
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07001 IVNS1ABP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IVNS1ABP RGD RGD:1306290
Macaca mulatta IVNS1ABP VGNC VGNC:99985
Mus musculus IVNS1ABP MGD MGI:2152389
Others IVNS1ABP NCBI
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