2. Gene
  3. Actn1 - actinin, alpha 1 Gene

Actn1 - actinin, alpha 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Actn1a; 3110023F10Rik

基因 ID: 109711 | 基因类型: protein coding

关于 Actn1

功能概要

Enables cytoskeletal protein binding activity; Integrin binding activity; and protein homodimerization activity. Involved in actin filament bundle assembly. Located in several cellular components, including Z disc; fascia adherens; and ruffle. Colocalizes with stress fiber. Is expressed in brain; heart; and testis. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 15. Orthologous to human ACTN1 (actinin alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Actn1 基因产物(4)

mRNA Protein Name
NM_001346669.2 NP_001333598.1 alpha-actinin-1 isoform 2
NM_001379075.1 NP_001366004.1 alpha-actinin-1 isoform 3
NM_001379076.1 NP_001366005.1 alpha-actinin-1 isoform 4
NM_134156.3 NP_598917.1 alpha-actinin-1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IDA
IDA: 通过直接分析推断
11223950 MGI
enables integrin binding IPI
IPI: 通过物理相互作用推断
11223950 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12223541 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
11223950 MGI
enables vinculin binding IDA
IDA: 通过直接分析推断
11223950 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament bundle assembly IDA
IDA: 通过直接分析推断
16043482 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
15665106 MGI
located in brush border IDA
IDA: 通过直接分析推断
22114352 MGI
located in fascia adherens IDA
IDA: 通过直接分析推断
11732910 MGI
located in ruffle IDA
IDA: 通过直接分析推断
17298598 MGI
located in sarcomere IDA
IDA: 通过直接分析推断
24364879 MGI
colocalizes with stress fiber IDA
IDA: 通过直接分析推断
23890175 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-actinin-1

F-actin cross-linking protein

alpha actinin 1a

non-muscle alpha-actinin-1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1728A Super-TDU (1-31) TFA Inhibitor 99.27% 否
HY-P1728 Super-TDU (1-31) Inhibitor / 否
HY-RS00223 ACTN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS17075 Actn1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS23519 Actn1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Actn1 NCBI NCBI:87
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