2. Gene
  3. GABARAP - GABA type A receptor-associated protein Gene

GABARAP - GABA type A receptor-associated protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：GABA A 型受体相关蛋白

种属: Homo sapiens

同用名: MM46; ATG8A; GABARAP-a

基因 ID: 11337 | 基因类型: protein coding

关于 GABARAP

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,240,008-7,242,449 (from NCBI)

This gene has 6 transcripts (splice variants), 133 orthologues and 6 paralogues. Ubiquitous expression in adrenal (RPKM 212.0), ovary (RPKM 206.1) and 25 other tissues.

功能概要

γ-氨基丁酸 A 受体 [GABA (A) 受体] 是介导抑制性神经传递的配体门控氯离子通道。该基因编码 GABA (A) 受体相关蛋白，其 N 末端带正电荷，与微管相关蛋白 1A 和 1B 的轻链 3 具有序列相似性。这种蛋白质通过介导与细胞骨架的相互作用来聚集神经递质受体。[RefSeq 提供，2008 年 7 月]

Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with LIGHT chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the Cytoskeleton. [provided by RefSeq, Jul 2008]

GABARAP 基因产物(1)

mRNA Protein Name
NM_007278.2 NP_009209.1 gamma-aminobutyric acid receptor-associated protein

GABARAP 蛋白结构

Atg8

Atg8: Autophagy protein Atg8 ubiquitin like (13 - 116)

  • 0
  • 100
  • 117 a.a.
蛋白主名 其他名称

gamma-aminobutyric acid receptor-associated protein

GABA(A) receptor-associated protein

重组 GABARAP 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70861 GABARAP Protein, Human (GST) Q6IAW1 (M1-L117) ≥95%
HY-P72639 GABARAP Protein, Human (His, Fc) Q6IAW1 (M1-L117) ≥95%
HY-P76942 GABARAP Protein, Human (His-MBP) O95166 (M1-L117) ≥95%

关联疾病

疾病名称 别名
Stiff-Person Syndrome

SPS

Stiff-Man Syndrome

Stiff Man Syndrome

Stiff Person Syndrome

Moersch-Woltman Syndrome

Sms

Stiff-Trunk Syndrome

Morsch Woltman Syndrome

Stiff Person Syndrome And Related Disorders

Stiff Person Spectrum Disorder

Classic Stiff Person Syndrome

Classic Sps

Focal Stiff Limb Syndrome

Focal Stiff-Person Syndrome

Stiff Leg Syndrome

Progressive Encephalomyelitis With Rigidity
Liver Carcinoma In Situ

Carcinoma In Situ Of Liver And Biliary System

Carcinoma In Situ Of Liver, Gallbladder And Bile Ducts
Machado-Joseph Disease

SCA3

MJD

Spinocerebellar Ataxia 3

Azorean Disease

Spinocerebellar Ataxia Type 3

Spinocerebellar Atrophy

Azorean Neurologic Disease

Spinopontine Atrophy

Nigrospinodentatal Degeneration

Spinocerebellar Atrophy Iii

Spinocerebellar Atrophy Type 3

Azorean Ataxia

Azorean Disease Of The Nervous System

Machado Disease

Nigro-Spino-Dentatal Degeneration With Nuclear Ophthalmoplegia

Disease, Machado-Joseph

Ataxia, Spinocerebellar
Retinitis Pigmentosa 84

RP84

Retinitis Pigmentosa, Type 84
Hereditary Sensory And Autonomic Neuropathy Type 1

Hereditary Sensory And Autonomic Neuropathy Type I

Hereditary Sensory Neuropathy-Deafness-Dementia Syndrome

Hsan1e

Hsan1

Dnmt1-Related Dementia, Deafness, And Sensory Neuropathy

Hsn1e

Hsnie

Hereditary Sensory Neuropathy Type Ie

Hereditary Sensory Neuropathy-Sensorineural Hearing Loss-Dementia Syndrome

Hereditary Sensory And Autonomic Neuropathy Type Ie

Hereditary Sensory And Autonomic Neuropathy Type 1e

Hereditary Sensory Neuropathy With Hearing Loss And Dementia

Dnmt1-Complex Disorder

Hereditary Sensory And Autonomic Neuropathy Type 1 With Dementia And Hearing Loss

Hsn Ie

Hereditary Sensory Autonomic Neuropathy, Type 1

Hsan1- [Hereditary Sensory And Autonomic Neuropathy Type I]
Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05201 GABARAP Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GABARAP RGD RGD:61911
Mus musculus GABARAP MGD MGI:1861742
Bos taurus GABARAP VGNC VGNC:29185
Canis familiaris GABARAP VGNC VGNC:41046
Felis catus GABARAP VGNC VGNC:62414
Others GABARAP NCBI
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