2. Gene
  3. Nr0b2 - nuclear receptor subfamily 0, group B, member 2 Gene

Nr0b2 - nuclear receptor subfamily 0, group B, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Shp

基因 ID: 117274 | 基因类型: protein coding

关于 Nr0b2

功能概要

Enables peroxisome proliferator activated receptor binding activity; retinoid X receptor binding activity; and Thyroid Hormone Receptor binding activity. Involved in several processes, including animal organ regeneration; bile acid and bile salt transport; and positive regulation of Insulin secretion. Part of protein-containing complex. Biomarker of alcoholic hepatitis; diabetes mellitus; and intrahepatic cholestasis. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR0B2 (nuclear receptor subfamily 0 group B member 2). [provided by Alliance of Genome Resources, Apr 2022]

Nr0b2 基因产物(1)

mRNA Protein Name
NM_057133.1 NP_476474.1 nuclear receptor subfamily 0 group B member 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nuclear retinoic acid receptor binding IPI
IPI: 通过物理相互作用推断
9003453 RGD
enables nuclear retinoid X receptor binding IPI
IPI: 通过物理相互作用推断
9003453 RGD
enables nuclear thyroid hormone receptor binding IPI
IPI: 通过物理相互作用推断
9003453 RGD
enables peroxisome proliferator activated receptor binding IPI
IPI: 通过物理相互作用推断
9003453 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
10648597 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
15904869 RGD
involved in bile acid and bile salt transport IEP
IEP: 通过表达模式推断
27939985 RGD
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
15860571 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
15860571 RGD
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
17259388 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
27939985 RGD
involved in response to glucose IMP
IMP: 通过突变表型推断
17259388 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
27939985 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of protein-containing complex IDA
IDA: 通过直接分析推断
10648597 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor subfamily 0 group B member 2

orphan nuclear receptor SHP

small heterodimer partner homologue

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09526 NR0B2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21668 Nr0b2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28186 Nr0b2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nr0b2 NCBI NCBI:8431
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