2. Gene
  3. Kif1b - kinesin family member 1B Gene

Kif1b - kinesin family member 1B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 117548 | 基因类型: protein coding

关于 Kif1b

功能概要

Enables several functions, including ATP hydrolysis activity; microtubule motor activity; and scaffold protein binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; dense core granule cytoskeletal transport; and response to rotenone. Located in several cellular components, including cytoplasmic vesicle; mitochondrion; and neuron projection. Biomarker of amyotrophic lateral sclerosis and synucleinopathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2A1; carcinoma (multiple); multiple sclerosis; neuroblastoma; and pheochromocytoma. Orthologous to human KIF1B (Kinesin family member 1B). [provided by Alliance of Genome Resources, Apr 2022]

Kif1b 基因产物(1)

mRNA Protein Name
NM_057200.2 NP_476548.1 kinesin-like protein KIF1B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP hydrolysis activity IDA
IDA: 通过直接分析推断
19744141 RGD
enables kinase binding IPI
IPI: 通过物理相互作用推断
12097473 RGD
enables microtubule motor activity IDA
IDA: 通过直接分析推断
19744141 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12204119 RGD
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
12097473 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in anterograde neuronal dense core vesicle transport IGI
IGI: 通过遗传相互作用推断
28426968 RGD
involved in cellular response to nerve growth factor stimulus IEP
IEP: 通过表达模式推断
24469107 RGD
involved in lysosome localization IMP
IMP: 通过突变表型推断
15086790 RGD
involved in organelle transport along microtubule IMP
IMP: 通过突变表型推断
15086790 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
24469107 RGD
involved in protein localization to cell periphery IMP
IMP: 通过突变表型推断
15086790 RGD
involved in response to rotenone IEP
IEP: 通过表达模式推断
23263842 RGD
involved in retrograde neuronal dense core vesicle transport IGI
IGI: 通过遗传相互作用推断
28426968 RGD
involved in transport along microtubule IDA
IDA: 通过直接分析推断
19744141 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
12204119 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
17571083 RGD
located in neuron projection IDA
IDA: 通过直接分析推断
12204119 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kinesin-like protein KIF1B

kinesin-family protein KIF1Bbeta3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07270 KIF1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21616 Kif1b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28134 Kif1b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kif1b NCBI NCBI:23095
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