2. Gene
  3. Apex1 - apurinic/apyrimidinic endonuclease 1 Gene

Apex1 - apurinic/apyrimidinic endonuclease 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: APE; Apex; HAP1; Ref-1

基因 ID: 11792 | 基因类型: protein coding

关于 Apex1

功能概要

Predicted to enable several functions, including DNA binding activity; NF-kappaB binding activity; and nuclease activity. Acts upstream of or within cell redox homeostasis. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; autopod; musculoskeletal system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ Cancer (multiple); spina bifida; and urinary bladder Cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Apex1 基因产物(1)

mRNA Protein Name
NM_009687.2 NP_033817.1 DNA-(apurinic or apyrimidinic site) endonuclease
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell redox homeostasis IDA
IDA: 通过直接分析推断
14594818 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
14594818 MGI
located in nucleus IDA
IDA: 通过直接分析推断
14594818 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA-(apurinic or apyrimidinic site) endonuclease

AP endonuclease 1

APEN

APEX nuclease

DNA-(apurinic or apyrimidinic site) lyase

redox factor-1

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00815 APEX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21480 Apex1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Apex1 NCBI NCBI:328
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