2. Gene
  3. ACOT4 - acyl-CoA thioesterase 4 Gene

ACOT4 - acyl-CoA thioesterase 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：酰基辅酶 A 硫酯酶 4

种属: Homo sapiens

同用名: PTE1B; PTE2B; PTE-Ib

基因 ID: 122970 | 基因类型: protein coding

关于 ACOT4

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:73,591,873-73,595,766 (from NCBI)

This gene has 1 transcript (splice variant), 389 orthologues and 4 paralogues. Broad expression in kidney (RPKM 4.8), liver (RPKM 2.8) and 21 other tissues.

功能概要

启用酰基辅酶 A 水解酶活性和琥珀酰辅酶 A 水解酶活性。参与羧酸代谢过程；饱和单羧酸代谢过程；和琥珀酰辅酶 A 代谢过程。位于过氧化物酶体中。 [由基因组资源联盟提供，2022 年 4 月]

Enables acyl-CoA hydrolase activity and succinyl-CoA hydrolase activity. Involved in carboxylic acid metabolic process; saturated monocarboxylic acid metabolic process; and succinyl-CoA metabolic process. Located in peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

ACOT4 基因产物(1)

mRNA Protein Name
NM_152331.4 NP_689544.3 peroxisomal succinyl-coenzyme A thioesterase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fatty acyl-CoA hydrolase activity IDA
IDA: 通过直接分析推断
16141203 GOA
enables succinyl-CoA hydrolase activity IDA
IDA: 通过直接分析推断
16141203 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acyl-CoA metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
NOT involved in butyrate metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in dicarboxylic acid catabolic process IDA
IDA: 通过直接分析推断
16141203 GOA
involved in dicarboxylic acid metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in long-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in saturated monocarboxylic acid metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in short-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in succinyl-CoA metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in unsaturated monocarboxylic acid metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
involved in very long-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
16940157 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in peroxisome IDA
IDA: 通过直接分析推断
16141203 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACOT4 蛋白结构

Bile_Hydr_Trans

Bile_Hydr_Trans: Acyl-CoA thioester hydrolase/BAAT N-terminal region (16 - 141)

BAAT_C

BAAT_C: BAAT / Acyl-CoA thioester hydrolase C terminal (203 - 411)

  • 0
  • 100
  • 200
  • 300
  • 421 a.a.
蛋白主名 其他名称

peroxisomal succinyl-coenzyme A thioesterase

PTE-2b

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-133180 YW1128 Inhibitor 99.38% 否
HY-RS00178 ACOT4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ACOT4 RGD RGD:1596753
Mus musculus ACOT4 MGD MGI:2159621
Canis familiaris ACOT4 VGNC VGNC:49744
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z