2. Gene
  3. Cyp8b1 - cytochrome P450, family 8, subfamily b, polypeptide 1 Gene

Cyp8b1 - cytochrome P450, family 8, subfamily b, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 13124 | 基因类型: protein coding

关于 Cyp8b1

功能概要

Predicted to enable sterol 12-alpha-hydroxylase activity. Involved in bile acid biosynthetic process and positive regulation of intestinal Cholesterol absorption. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including liver; lung; skeletal muscle; spleen; and testis. Orthologous to human CYP8B1 (Cytochrome P450 family 8 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp8b1 基因产物(1)

mRNA Protein Name
NM_010012.3 NP_034142.3 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bile acid biosynthetic process IMP
IMP: 通过突变表型推断
12393855 MGI
involved in positive regulation of intestinal cholesterol absorption IDA
IDA: 通过直接分析推断
12393855 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase

7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase

CYPVIIIB1

cytochrome P450 8B1

cytochrome P450, 8b1, sterol 12 alpha-hydrolase

sterol 12-alpha-hydrolase

sterol 12-alpha-hydroxylase

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-113259 7α-Hydroxy-4-cholesten-3-one 99.60% 否
HY-113259S 7α-Hydroxy-4-cholesten-3-one-d7 ≥98.0% 否
HY-113259R 7α-Hydroxy-4-cholesten-3-one (Standard) / 否
HY-RS03489 CYP8B1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS17779 Cyp8b1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS24246 Cyp8b1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp8b1 NCBI NCBI:1582
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