1. Gene
  2. Pofut1 - protein O-fucosyltransferase 1 Gene

Pofut1 - protein O-fucosyltransferase 1 Gene

种属: Mus musculus

同用名: O-FucT-1

基因 ID: 140484 | 基因类型: protein coding

关于 Pofut1

功能概要

Predicted to enable peptide-O-fucosyltransferase activity. Involved in Notch signaling pathway. Acts upstream of or within circulatory system development; nervous system development; and somitogenesis. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in brain; embryo; skeletal muscle tissue; and skeletal musculature. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Orthologous to human POFUT1 (protein O-fucosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pofut1 基因产物(1)

mRNA Protein Name
NM_080463.4 NP_536711.3 GDP-fucose protein O-fucosyltransferase 1 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Notch signaling pathway IMP
IMP: 通过突变表型推断
12697902 MGI
involved in Notch signaling pathway IMP
IMP: 通过突变表型推断
19161597 MGI
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
12697902 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
12697902 MGI
acts upstream of or within nervous system development IMP
IMP: 通过突变表型推断
12697902 MGI
acts upstream of or within somitogenesis IMP
IMP: 通过突变表型推断
12697902 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

GDP-fucose protein O-fucosyltransferase 1

peptide-O-fucosyltransferase 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pofut1 NCBI NCBI:23509