2. Gene
  3. RIMS4 - regulating synaptic membrane exocytosis 4 Gene

RIMS4 - regulating synaptic membrane exocytosis 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：调节突触膜胞吐作用 4

种属: Homo sapiens

同用名: RIM4; RIM 4; RIM-4; C20orf190; RIM4gamma; RIM4-gamma

基因 ID: 140730 | 基因类型: protein coding

关于 RIMS4

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:44,751,808-44,810,546 (from NCBI)

This gene has 2 transcripts (splice variants), 197 orthologues and 4 paralogues. Biased expression in brain (RPKM 10.7), testis (RPKM 10.4) and 8 other tissues.

功能概要

预测启用跨膜转运蛋白结合活性。预计参与膜电位的调节；突触组织的调节；和突触小泡胞吐的调节。预测位于突触膜。预计在谷氨酸能突触中活跃。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable transmembrane transporter binding activity. Predicted to be involved in regulation of membrane potential; regulation of synapse organization; and regulation of synaptic vesicle exocytosis. Predicted to be located in synaptic membrane. Predicted to be active in glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2022]

RIMS4 基因产物(2)

mRNA Protein Name
NM_001205317.2 NP_001192246.1 regulating synaptic membrane exocytosis protein 4 isoform 1
NM_182970.4 NP_892015.1 regulating synaptic membrane exocytosis protein 4 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RIMS4 蛋白结构

C2

C2: C2 domain (130 - 216)

  • 0
  • 100
  • 200
  • 269 a.a.
蛋白主名 其他名称

regulating synaptic membrane exocytosis protein 4

RIM4 gamma

关联疾病

疾病名称 别名
Partial Trisomy Distal 4q

Distal Trisomy 4q

Chromosome 4, Partial Trisomy 4q

Distal 4q Trisomy

Dup Syndrome, Partial

Duplication 4q Syndrome, Partial

Partial Trisomy 4q Syndrome

Distal Duplication 4q

Telomeric Duplication 4q

Trisomy 4qter
Heimler Syndrome 2

HMLR2

Peroxisome Biogenesis Disorder 4c

Pbd4c

Peroxisomal Biogenesis Disorder 4c

Heimler Syndrome, Type 2
Cone-Rod Dystrophy 7

CORD7

Dystrophy, Cone-Rod, Type 7

Retinitis Pigmentosa 7
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11981 RIMS4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus RIMS4 MGD MGI:2674366
Canis familiaris RIMS4 VGNC VGNC:45585
Rattus norvegicus RIMS4 RGD RGD:628695
Bos taurus RIMS4 VGNC VGNC:33974
Macaca mulatta RIMS4 VGNC VGNC:76743
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