KIF18B - kinesin family member 18B Gene

中文名称：驱动蛋白家族成员 18B

种属: Homo sapiens

基因 ID: 146909 | 基因类型: protein coding

关于 KIF18B

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:44,924,711-44,947,773 (from NCBI)

This gene has 4 transcripts (splice variants), 118 orthologues and 41 paralogues. Broad expression in bone marrow (RPKM 3.6), lymph node (RPKM 2.4) and 14 other tissues.

功能概要

启用细胞骨架运动活动和驱动蛋白结合活动。参与微管解聚；有丝分裂细胞周期；和细胞分裂的调节。位于胞质溶胶中；微管;和核体。 [由基因组资源联盟提供，2022 年 4 月]

Enables cytoskeletal motor activity and Kinesin binding activity. Involved in microtubule depolymerization; mitotic cell cycle; and regulation of cell division. Located in cytosol; microtubule; and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

KIF18B 基因产物(2)

mRNA	Protein	Name
NM_001264573.2	NP_001251503.1	kinesin-like protein KIF18B isoform 2
NM_001265577.2	NP_001252506.1	kinesin-like protein KIF18B isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables cytoskeletal motor activity	IDA IDA: 通过直接分析推断	21820309	GOA
enables kinesin binding	IPI IPI: 通过物理相互作用推断	21820309	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	21820309	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in microtubule depolymerization	IDA IDA: 通过直接分析推断	21820309	GOA
involved in mitotic cell cycle	IDA IDA: 通过直接分析推断	20600703	GOA
involved in regulation of cell division	IDA IDA: 通过直接分析推断	20600703	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in astral microtubule	IDA IDA: 通过直接分析推断	21820309	GOA
located in cytoplasm	IDA IDA: 通过直接分析推断	20600703	GOA
located in microtubule plus-end	IDA IDA: 通过直接分析推断	21820309	GOA
located in nucleus	IDA IDA: 通过直接分析推断	20600703	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KIF18B 蛋白结构

Kinesin

0
200
400
600
800
852 a.a.

蛋白主名

其他名称

kinesin-like protein KIF18B

关联疾病

疾病名称

别名

Filippi Syndrome

Scott Craniodigital Syndrome With Mental Retardation	Type 1 Syndactyly-Microcephaly-Intellectual Disability Syndrome
FLPIS	Scott Bryant Graham Syndrome
Craniodigital-Intellectual Disability Syndrome	Scott Craniodigital Syndrome
Scott-Bryant-Graham Syndrome	Syndactyly, Type I, With Microcephaly And Mental Retardation
Syndactyly Type I With Microcephaly And Intellectual Disability	Unusual Facial Appearance, Microcephaly, Growth And Intellectual Disability And Syndactyly
Craniodigital Syndrome With Intellectual Disability	Craniodigital Syndrome-Intellectual Disability Syndrome
Craniodigital Syndrome-Intellectual Disability, Scott Type	Intellectual Disability-Craniodigital Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS07268	KIF18B Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	KIF18B	RGD	RGD:1310360
Canis familiaris	KIF18B	VGNC	VGNC:42388
Bos taurus	KIF18B	VGNC	VGNC:30588
Mus musculus	KIF18B	MGD	MGI:2446979
Felis catus	KIF18B	VGNC	VGNC:63108
Macaca mulatta	KIF18B	VGNC	VGNC:99162

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

KIF18B - kinesin family member 18B Gene

关于 KIF18B

功能概要

KIF18B 基因产物(2)

KIF18B 蛋白结构

关联疾病

直系同源

热门区域

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KIF18B - kinesin family member 18B Gene

关于 KIF18B

功能概要

KIF18B 基因产物(2)

KIF18B 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z