1. Gene
  2. Hint1 - histidine triad nucleotide binding protein 1 Gene

Hint1 - histidine triad nucleotide binding protein 1 Gene

种属: Mus musculus

同用名: Hint; Ipk1; PKCI-1; PRKCNH1

基因 ID: 15254 | 基因类型: protein coding

关于 Hint1

功能概要

Predicted to enable adenosine 5'-monophosphoramidase activity. Involved in positive regulation of calcium-mediated signaling and protein desumoylation. Located in nucleus. Is expressed in several structures, including brain; colon; genitourinary system; mammary gland; and spleen. Human ortholog(s) of this gene implicated in Gamstorp-Wohlfart syndrome. Orthologous to human HINT1 (histidine triad nucleotide binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Hint1 基因产物(1)

mRNA Protein Name
NM_008248.3 NP_032274.1 adenosine 5'-monophosphoramidase HINT1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables deSUMOylase activity IDA
IDA: 通过直接分析推断
31088288 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
31088288 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of calcium-mediated signaling IMP
IMP: 通过突变表型推断
23576580 MGI
involved in protein desumoylation IMP
IMP: 通过突变表型推断
31088288 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9770345 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

adenosine 5'-monophosphoramidase HINT1

PKC inhibitor/ interacting protein

adenosine 5'-monophosphoramidase

desumoylating isopeptidase HINT1

protein kinase C inhibitor 1

protein kinase C-interacting protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hint1 NCBI NCBI:3094