1. Gene
  2. Tnfrsf1b - TNF receptor superfamily member 1B Gene

Tnfrsf1b - TNF receptor superfamily member 1B Gene

种属: Rattus norvegicus

同用名: Tnfr2

基因 ID: 156767 | 基因类型: protein coding

关于 Tnfrsf1b

功能概要

Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to tumor necrosis factor; and response to lipopolysaccharide. Located in several cellular components, including neuronal cell body; perinuclear region of cytoplasm; and varicosity. Used to study visual epilepsy. Biomarker of Crohn's disease; myocardial infarction; sciatic neuropathy; and ureteral obstruction. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Orthologous to human TNFRSF1B (TNF Receptor Superfamily member 1B). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf1b 基因产物(1)

mRNA Protein Name
NM_130426.4 NP_569110.1 tumor necrosis factor receptor superfamily member 1B precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables tumor necrosis factor receptor activity IDA
IDA: 通过直接分析推断
12376316 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to growth factor stimulus IEP
IEP: 通过表达模式推断
20715153 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
11324713 RGD
involved in immune response IDA
IDA: 通过直接分析推断
12376316 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
21195213 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
11240015 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
20715153 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
20715153 RGD
located in varicosity IDA
IDA: 通过直接分析推断
20715153 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor receptor superfamily member 1B

TNF-R2

TNF-RII

TNFR-II

p75

p80 TNF-alpha receptor

tumor necrosis factor receptor 2

tumor necrosis factor receptor superfamily, member 1b

tumor necrosis factor receptor type II

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnfrsf1b NCBI NCBI:7133
Mus musculus Tnfrsf1b NCBI NCBI:21938
Macaca mulatta Tnfrsf1b NCBI NCBI:715454