2. Gene
  3. Lamb2 - laminin, beta 2 Gene

Lamb2 - laminin, beta 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Lams; npht; Lamb-2

基因 ID: 16779 | 基因类型: protein coding

关于 Lamb2

功能概要

Enables Integrin binding activity. Acts upstream of or within several processes, including metanephric glomerulus development; neurogenesis; and visual perception. Located in basement membrane and neuromuscular junction. Part of laminin-3 complex. Is active in synaptic cleft. Is expressed in several structures, including Reichert's membrane; alimentary system; brain; decidua; and liver. Used to study Pierson syndrome and nephrosis. Human ortholog(s) of this gene implicated in Pierson syndrome and nephrotic syndrome type 5. Orthologous to human LAMB2 (laminin subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022]

Lamb2 基因产物(3)

mRNA Protein Name
NM_001411228.1 NP_001398157.1 laminin subunit beta-2 precursor
NM_001411229.1 NP_001398158.1 laminin subunit beta-2 precursor
NM_008483.4 NP_032509.2 laminin subunit beta-2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IPI
IPI: 通过物理相互作用推断
20566382 MGI
enables structural constituent of synapse-associated extracellular matrix IDA
IDA: 通过直接分析推断
17189701 MGI
enables structural constituent of synapse-associated extracellular matrix IEP
IEP: 通过表达模式推断
17189701 MGI
enables structural constituent of synapse-associated extracellular matrix IMP
IMP: 通过突变表型推断
17189701 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Schwann cell development IDA
IDA: 通过直接分析推断
9641682 MGI
acts upstream of or within astrocyte development IGI
IGI: 通过遗传相互作用推断
19907020 MGI
acts upstream of or within axon extension involved in regeneration IMP
IMP: 通过突变表型推断
9396756 MGI
acts upstream of or within axon guidance IGI
IGI: 通过遗传相互作用推断
19295126 MGI
acts upstream of or within cell morphogenesis IGI
IGI: 通过遗传相互作用推断
19907020 MGI
acts upstream of or within metanephric glomerular basement membrane development IMP
IMP: 通过突变表型推断
7670489 MGI
acts upstream of or within metanephric podocyte development IMP
IMP: 通过突变表型推断
16886065 MGI
acts upstream of or within neuromuscular junction development IMP
IMP: 通过突变表型推断
7885444 MGI
acts upstream of or within neuron projection development IDA
IDA: 通过直接分析推断
20566382 MGI
acts upstream of or within retina development in camera-type eye IGI
IGI: 通过遗传相互作用推断
19907020 MGI
acts upstream of or within synapse organization IMP
IMP: 通过突变表型推断
17189701 MGI
acts upstream of or within visual perception IGI
IGI: 通过遗传相互作用推断
19907020 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
7670489 MGI
part of laminin complex IDA
IDA: 通过直接分析推断
8034675 MGI
part of laminin-3 complex IDA
IDA: 通过直接分析推断
20566382 MGI
is active in neuromuscular junction IDA
IDA: 通过直接分析推断
9396756 MGI
located in synapse IDA
IDA: 通过直接分析推断
17189701 MGI
is active in synaptic cleft IDA
IDA: 通过直接分析推断
9396756 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

laminin subunit beta-2

Laminin S

S-LAM beta

S-laminin subunit beta

laminin-11 subunit beta

laminin-14 subunit beta

laminin-15 subunit beta

laminin-3 subunit beta

laminin-4 subunit beta

laminin-7 subunit beta

laminin-9 subunit beta

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07503 LAMB2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07506 LAMC1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07716 LMNB2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20440 Lamc1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS21625 Lamb2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS28143 Lamb2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lamb2 NCBI NCBI:3913
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