2. Gene
  3. Lamp2 - lysosomal-associated membrane protein 2 Gene

Lamp2 - lysosomal-associated membrane protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mac3; LGP-B; CD107b; Lamp-2; Lamp II; Lamp-2a; Lamp-2b; Lamp-2c

基因 ID: 16784 | 基因类型: protein coding

关于 Lamp2

功能概要

Enables protein domain specific binding activity. Involved in several processes, including autophagosome maturation; protein stabilization; and protein targeting to lysosome involved in chaperone-mediated Autophagy. Acts upstream of or within muscle cell cellular homeostasis. Located in late endosome membrane; lysosomal membrane; and phagocytic vesicle membrane. Is integral component of autophagosome membrane. Is expressed in central nervous system; egg cylinder; lung; and retina. Used to study Danon disease. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Orthologous to human LAMP2 (lysosomal associated membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Lamp2 基因产物(3)

mRNA Protein Name
NM_001017959.2 NP_001017959.1 lysosome-associated membrane glycoprotein 2 isoform 1 precursor
NM_001290485.2 NP_001277414.1 lysosome-associated membrane glycoprotein 2 isoform 3 precursor
NM_010685.4 NP_034815.2 lysosome-associated membrane glycoprotein 2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21194361 MGI
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
22641697 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in autophagosome maturation IMP
IMP: 通过突变表型推断
27628032 MGI
involved in autophagy IMP
IMP: 通过突变表型推断
12221139 MGI
involved in cellular response to starvation IMP
IMP: 通过突变表型推断
27628032 MGI
involved in chaperone-mediated autophagy IGI
IGI: 通过遗传相互作用推断
18644871 MGI
acts upstream of or within chaperone-mediated autophagy IMP
IMP: 通过突变表型推断
18579532 MGI
involved in chaperone-mediated autophagy IMP
IMP: 通过突变表型推断
27628032 MGI
acts upstream of or within muscle cell cellular homeostasis IMP
IMP: 通过突变表型推断
20060297 MGI
involved in protein stabilization IMP
IMP: 通过突变表型推断
22641697 MGI
involved in protein targeting IMP
IMP: 通过突变表型推断
12221139 MGI
involved in protein targeting to lysosome involved in chaperone-mediated autophagy IMP
IMP: 通过突变表型推断
27628032 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in autophagosome membrane IDA
IDA: 通过直接分析推断
12221139 MGI
located in late endosome IDA
IDA: 通过直接分析推断
14668490 MGI
located in late endosome membrane IDA
IDA: 通过直接分析推断
21896273 MGI
located in lysosomal membrane IDA
IDA: 通过直接分析推断
18022370 MGI
is active in lysosome IDA
IDA: 通过直接分析推断
17185018 MGI
located in lysosome IDA
IDA: 通过直接分析推断
12775715 MGI
located in phagocytic vesicle membrane IMP
IMP: 通过突变表型推断
9670047 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysosome-associated membrane glycoprotein 2

CD107 antigen-like family member B

lysosomal membrane glycoprotein 2

lysosomal membrane glycoprotein type B

重组 Lamp2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74781 LAMP2/CD107b Protein, Mouse (HEK293, His) P17047 (L26-N379) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-134923 CA77.1 Inducer 99.98% 否
HY-112483 QX77 Inducer 99.48% 否
HY-RS07510 LAMP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17112 Lamp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23557 Lamp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lamp2 NCBI NCBI:3920
Macaca fascicularis Lamp2 NCBI NCBI:102119735
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z