1. Gene
  2. Meox1 - mesenchyme homeobox 1 Gene

Meox1 - mesenchyme homeobox 1 Gene

种属: Mus musculus

同用名: Mox1; Mox-1; D330041M02Rik

基因 ID: 17285 | 基因类型: protein coding

关于 Meox1

功能概要

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in sclerotome development. Acts upstream of or within positive regulation of transcription by RNA polymerase II and somite specification. Located in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; embryo mesenchyme; genitourinary system; heart; and musculoskeletal system. Human ortholog(s) of this gene implicated in Klippel-Feil syndrome 2. Orthologous to human MEOX1 (mesenchyme homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Meox1 基因产物(1)

mRNA Protein Name
NM_010791.3 NP_034921.1 homeobox protein MOX-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15024065 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
15024065 MGI
enables HMG box domain binding IPI
IPI: 通过物理相互作用推断
16582099 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15024065 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
15024065 MGI
enables sequence-specific DNA binding IMP
IMP: 通过突变表型推断
22206000 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15024065 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15024065 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
15024065 MGI
involved in sclerotome development IMP
IMP: 通过突变表型推断
15024065 MGI
involved in somite development IMP
IMP: 通过突变表型推断
19520072 MGI
acts upstream of or within somite specification IGI
IGI: 通过遗传相互作用推断
12925591 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
22206000 MGI
located in nucleus IDA
IDA: 通过直接分析推断
22206000 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

homeobox protein MOX-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Meox1 NCBI NCBI:4222