2. Gene
  3. Pabpc1 - poly(A) binding protein, cytoplasmic 1 Gene

Pabpc1 - poly(A) binding protein, cytoplasmic 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PABP; ePAB; Pabp1; PabpI; Pabpl1

基因 ID: 18458 | 基因类型: protein coding

关于 Pabpc1

功能概要

Predicted to enable RNA binding activity and protein C-terminus binding activity. Involved in gene silencing by RNA; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Located in cytoplasm and synapse. Is expressed in several structures, including central nervous system; early conceptus; gonad; gut; and sensory organ. Orthologous to several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1). [provided by Alliance of Genome Resources, Apr 2022]

Pabpc1 基因产物(1)

mRNA Protein Name
NM_008774.3 NP_032800.2 polyadenylate-binding protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17927953 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IMP
IMP: 通过突变表型推断
19716330 MGI
involved in positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IMP
IMP: 通过突变表型推断
19716330 MGI
involved in regulatory ncRNA-mediated gene silencing IMP
IMP: 通过突变表型推断
19716330 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
18625844 MGI
is active in synapse EXP
EXP: 通过实验结果推断
16452087 MGI
is active in synapse IDA
IDA: 通过直接分析推断
16452087 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

polyadenylate-binding protein 1

PABP-1

poly(A)-binding protein 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09948 PABPC1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS19518 Pabpc1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26013 Pabpc1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990727 Alextatug / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pabpc1 NCBI NCBI:26986
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