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  3. Pou3f2 - POU domain, class 3, transcription factor 2 Gene

Pou3f2 - POU domain, class 3, transcription factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Brn2; Otf7; Brn-2; OTF-7; oct-7; 9430075J19Rik; A230098E07Rik

基因 ID: 18992 | 基因类型: protein coding

关于 Pou3f2

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in neuron differentiation and regulation of gene expression. Acts upstream of or within several processes, including epidermis development; nervous system development; and regulation of axonogenesis. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; eye; future brain; genitourinary system; and thymus. Orthologous to human POU3F2 (POU class 3 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Pou3f2 基因产物(1)

mRNA Protein Name
NM_008899.2 NP_032925.1 POU domain, class 3, transcription factor 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12782656 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15465489 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
24243019 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15465489 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24643061 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17141158 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Schwann cell development IGI
IGI: 通过遗传相互作用推断
12782656 MGI
acts upstream of or within cerebral cortex radially oriented cell migration IGI
IGI: 通过遗传相互作用推断
12130536 MGI
acts upstream of or within epidermis development IMP
IMP: 通过突变表型推断
8543156 MGI
acts upstream of or within forebrain astrocyte development IMP
IMP: 通过突变表型推断
8543156 MGI
acts upstream of or within forebrain ventricular zone progenitor cell division IGI
IGI: 通过遗传相互作用推断
12130536 MGI
acts upstream of or within hypothalamus cell differentiation IMP
IMP: 通过突变表型推断
8543156 MGI
acts upstream of or within myelination in peripheral nervous system IGI
IGI: 通过遗传相互作用推断
12782656 MGI
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
23069940 MGI
involved in nervous system development IDA
IDA: 通过直接分析推断
24243019 MGI
acts upstream of or within neuroendocrine cell differentiation IMP
IMP: 通过突变表型推断
8543156 MGI
acts upstream of or within neurohypophysis development IMP
IMP: 通过突变表型推断
8543156 MGI
involved in neuron development IDA
IDA: 通过直接分析推断
24243019 MGI
acts upstream of or within neuron differentiation IDA
IDA: 通过直接分析推断
17141158 MGI
involved in neuron differentiation IDA
IDA: 通过直接分析推断
24243019 MGI
involved in neuron fate commitment IDA
IDA: 通过直接分析推断
24243019 MGI
involved in neuron fate specification IDA
IDA: 通过直接分析推断
24243019 MGI
acts upstream of or within positive regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
8543156 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15465489 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
17141158 MGI
acts upstream of or within regulation of axonogenesis IMP
IMP: 通过突变表型推断
8543156 MGI
acts upstream of or within regulation of cell differentiation IMP
IMP: 通过突变表型推断
8593698 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15465489 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
24243019 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12782656 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
12782656 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

POU domain, class 3, transcription factor 2

brain-2 class III POU-domain protein

brain-specific homeobox/POU domain protein 2

nervous system-specific octamer-binding transcription factor N-Oct-3

octamer-binding protein 7

octamer-binding transcription factor 7

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10901 POU3F2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS21172 Pou3f2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS27689 Pou3f2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pou3f2 NCBI NCBI:5454
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