2. Gene
  3. Txk - TXK tyrosine kinase Gene

Txk - TXK tyrosine kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rlk; Btkl; PTK4; PTK-RL-18; A130089B16Rik

基因 ID: 22165 | 基因类型: protein coding

关于 Txk

功能概要

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including T cell receptor signaling pathway; activation of Phospholipase C activity; and positive regulation of cytokine production. Acts upstream of or within NK T cell differentiation. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including hemolymphoid system; lung; male reproductive gland or organ; stomach mesentery; and vertebral axis musculature. Orthologous to human TXK (TXK tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Txk 基因产物(4)

mRNA Protein Name
NM_001122754.2 NP_001116226.1 tyrosine-protein kinase TXK isoform 1
NM_001289494.1 NP_001276423.1 tyrosine-protein kinase TXK isoform 3
NM_001289495.1 NP_001276424.1 tyrosine-protein kinase TXK isoform 4
NM_013698.3 NP_038726.2 tyrosine-protein kinase TXK isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within NK T cell differentiation IGI
IGI: 通过遗传相互作用推断
18292523 MGI
involved in T cell receptor signaling pathway IMP
IMP: 通过突变表型推断
10213685 MGI
involved in adaptive immune response IMP
IMP: 通过突变表型推断
10213685 MGI
acts upstream of or within interleukin-4 production IGI
IGI: 通过遗传相互作用推断
18292523 MGI
involved in positive regulation of cytokine production IMP
IMP: 通过突变表型推断
10213685 MGI
acts upstream of or within type II interferon production IGI
IGI: 通过遗传相互作用推断
18292523 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tyrosine-protein kinase TXK

resting lymphocyte kinase

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-10644 Lck inhibitor 2 Inhibitor 99.73% 否
HY-174129 TM471-1 / 否
HY-145373 BMS-986143 Inhibitor / 否
HY-RS15285 TXK Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-D2415 BODIPY-FL staurosporine / 否
HY-RS22085 Txk Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS28605 Txk Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Txk NCBI NCBI:7294
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