1. Gene
  2. Vim - vimentin Gene

Vim - vimentin Gene

种属: Mus musculus

基因 ID: 22352 | 基因类型: protein coding

关于 Vim

功能概要

Enables RNA binding activity. A structural constituent of Cytoskeleton and structural constituent of eye lens. Involved in intermediate filament organization and positive regulation of gene expression. Acts upstream of or within several processes, including SMAD protein signal transduction; astrocyte differentiation; and cellular response to interferon-gamma. Located in several cellular components, including cell leading edge; intermediate filament; and phagocytic vesicle. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Used to study cataract 30. Human ortholog(s) of this gene implicated in atherosclerosis; autoimmune disease (multiple); and cataract 30. Orthologous to human VIM (vimentin). [provided by Alliance of Genome Resources, Apr 2022]

Vim 基因产物(1)

mRNA Protein Name
NM_011701.4 NP_035831.2 vimentin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IPI
IPI: 通过物理相互作用推断
23239537 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11895474 MGI
enables structural constituent of cytoskeleton IMP
IMP: 通过突变表型推断
12177195 MGI
enables structural constituent of eye lens IDA
IDA: 通过直接分析推断
15037121 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell leading edge IDA
IDA: 通过直接分析推断
15958512 MGI
located in cell projection IDA
IDA: 通过直接分析推断
10989258 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
15965470 MGI
located in intermediate filament IDA
IDA: 通过直接分析推断
2493000 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
16052496 MGI
located in phagocytic vesicle IDA
IDA: 通过直接分析推断
19144319 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
18178558 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

vimentin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vim NCBI NCBI:7431