2. Gene
  3. Man1b1 - mannosidase, alpha, class 1B, member 1 Gene

Man1b1 - mannosidase, alpha, class 1B, member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gm108; ERMan1; MANA-ER; E430019H13Rik

基因 ID: 227619 | 基因类型: protein coding

关于 Man1b1

功能概要

Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Acts upstream of or within ubiquitin-dependent ERAD pathway. Predicted to be located in cytoplasmic vesicle and endoplasmic reticulum quality control compartment. Predicted to be active in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human MAN1B1 (mannosidase alpha class 1B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Man1b1 基因产物(1)

mRNA Protein Name
NM_001029983.2 NP_001025154.1 endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IMP
IMP: 通过突变表型推断
15294975 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within ERAD pathway IMP
IMP: 通过突变表型推断
15294975 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

ER alpha-1,2-mannosidase

ER mannosidase 1

man9GlcNAc2-specific-processing alpha-mannosidase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08006 MAN1B1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS19789 Man1b1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26285 Man1b1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Man1b1 NCBI NCBI:11253
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