2. Gene
  3. Gbp5 - guanylate binding protein 5 Gene

Gbp5 - guanylate binding protein 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gbp5a; 5330409J06Rik

基因 ID: 229898 | 基因类型: protein coding

关于 Gbp5

功能概要

Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Involved in positive regulation of cytokine production and positive regulation of innate immune response. Acts upstream of or within cellular response to interferon-gamma and response to bacterium. Located in cytoplasmic vesicle. Orthologous to human GBP5 (guanylate binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Gbp5 基因产物(1)

mRNA Protein Name
NM_153564.2 NP_705792.2 guanylate-binding protein 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22461501 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of innate immune response IMP
IMP: 通过突变表型推断
24739961 MGI
involved in cellular response to lipopolysaccharide IMP
IMP: 通过突变表型推断
24715728 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: 通过直接分析推断
18025219 MGI
involved in cytolysis in another organism IDA
IDA: 通过直接分析推断
25774715 MGI
involved in cytolysis in another organism IMP
IMP: 通过突变表型推断
24715728 MGI
involved in defense response to bacterium IDA
IDA: 通过直接分析推断
25774715 MGI
involved in defense response to bacterium IMP
IMP: 通过突变表型推断
24715728 MGI
involved in positive regulation of AIM2 inflammasome complex assembly IDA
IDA: 通过直接分析推断
25774715 MGI
involved in positive regulation of cytokine production involved in inflammatory response IMP
IMP: 通过突变表型推断
22461501 MGI
involved in positive regulation of innate immune response IMP
IMP: 通过突变表型推断
22461501 MGI
involved in positive regulation of interleukin-1 beta production IMP
IMP: 通过突变表型推断
22461501 MGI
involved in positive regulation of interleukin-18 production IMP
IMP: 通过突变表型推断
22461501 MGI
involved in positive regulation of pyroptotic inflammatory response IDA
IDA: 通过直接分析推断
25774715 MGI
involved in positive regulation of pyroptotic inflammatory response IMP
IMP: 通过突变表型推断
24715728 MGI
involved in protein targeting IDA
IDA: 通过直接分析推断
27693356 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
18025219 MGI
is active in symbiont cell surface IDA
IDA: 通过直接分析推断
27693356 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

guanylate-binding protein 5

GBP-5

GTP-binding protein 5

guanine nucleotide-binding protein 5

guanylate nucleotide binding protein 5

muGBP-5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05311 GBP5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS18761 Gbp5 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS25248 Gbp5 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gbp5 NCBI NCBI:115362
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