1. Gene
  2. Micall2 - MICAL-like 2 Gene

Micall2 - MICAL-like 2 Gene

种属: Mus musculus

同用名: JRAB; MICAL-L2; mFLJ00139; A930021H16Rik

基因 ID: 231830 | 基因类型: protein coding

关于 Micall2

功能概要

Enables cytoskeletal protein binding activity and small GTPase binding activity. Involved in several processes, including actin Cytoskeleton organization; bicellular tight junction assembly; and substrate adhesion-dependent cell spreading. Acts upstream of or within endocytic recycling. Located in several cellular components, including actin filament bundle; bicellular tight junction; and recycling endosome. Colocalizes with stress fiber. Is expressed in several structures, including chondrocranium; liver lobe; medulla oblongata basal plate; submandibular gland primordium; and vibrissa. Orthologous to human MICALL2 (MICAL like 2). [provided by Alliance of Genome Resources, Apr 2022]

Micall2 基因产物(1)

mRNA Protein Name
NM_174850.3 NP_777275.2 MICAL-like protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IDA
IDA: 通过直接分析推断
18332111 MGI
enables actinin binding IPI
IPI: 通过物理相互作用推断
23890175 MGI
enables filamin binding IDA
IDA: 通过直接分析推断
23890175 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16525024 MGI
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
18094055 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin cytoskeleton organization IMP
IMP: 通过突变表型推断
23890175 MGI
involved in actin filament polymerization IMP
IMP: 通过突变表型推断
20008558 MGI
involved in bicellular tight junction assembly IMP
IMP: 通过突变表型推断
18094055 MGI
acts upstream of or within endocytic recycling IDA
IDA: 通过直接分析推断
16525024 MGI
involved in endocytic recycling IMP
IMP: 通过突变表型推断
18094055 MGI
involved in neuron projection development IMP
IMP: 通过突变表型推断
20008558 MGI
involved in substrate adhesion-dependent cell spreading IMP
IMP: 通过突变表型推断
23890175 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin filament bundle IDA
IDA: 通过直接分析推断
16525024 MGI
located in bicellular tight junction IDA
IDA: 通过直接分析推断
16525024 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
18332111 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
18094055 MGI
located in recycling endosome IDA
IDA: 通过直接分析推断
18094055 MGI
colocalizes with stress fiber IDA
IDA: 通过直接分析推断
23890175 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

MICAL-like protein 2

junctional Rab13-binding protein

molecule interacting with CasL-like 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Micall2 NCBI NCBI:79778