1. Gene
  2. Hax1 - HCLS1 associated X-1 Gene

Hax1 - HCLS1 associated X-1 Gene

种属: Mus musculus

同用名: HAX-1; Hs1bp1; SIG-111; Silg111; mHAX-1s; HSP1BP-1

基因 ID: 23897 | 基因类型: protein coding

关于 Hax1

功能概要

Predicted to enable interleukin-1 binding activity; protein N-terminus binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of actin Cytoskeleton organization. Predicted to act upstream of or within cell surface receptor signaling pathway. Located in several cellular components, including actin cytoskeleton; lamellipodium; and sarcoplasmic reticulum. Is expressed in coelomic epithelium of testis; ovary; and testis mesenchyme. Human ortholog(s) of this gene implicated in severe congenital neutropenia 3. Orthologous to human HAX1 (HCLS1 associated protein X-1). [provided by Alliance of Genome Resources, Apr 2022]

Hax1 基因产物(3)

mRNA Protein Name
NM_001282032.1 NP_001268961.1 HCLS1-associated protein X-1 isoform 2
NM_001310681.1 NP_001297610.1 HCLS1-associated protein X-1 isoform 3
NM_011826.4 NP_035956.1 HCLS1-associated protein X-1 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10760273 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
10760273 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
10760273 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
10760273 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
10760273 MGI
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
26915802 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
9058808 MGI
located in sarcoplasmic reticulum IDA
IDA: 通过直接分析推断
19920172 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

HCLS1-associated protein X-1

HS1 binding protein

HS1-associated protein X-1

HS1-associating protein X-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hax1 NCBI NCBI:10456