1. Gene
  2. Arid1b - AT rich interactive domain 1B (SWI-like) Gene

Arid1b - AT rich interactive domain 1B (SWI-like) Gene

种属: Mus musculus

同用名: Ardi1b; BAF250B; mKIAA1235; 8030481M12; 9330189K18Rik; B230217J03Rik

基因 ID: 239985 | 基因类型: protein coding

关于 Arid1b

功能概要

Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Acts upstream of or within dendritic cell dendrite assembly; dendritic spine development; and neuron-neuron synaptic transmission. Located in nucleus. Part of nBAF complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Coffin-Siris syndrome 1 and autism spectrum disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome; Coffin-Siris syndrome 1; intellectual disability; lung non-small cell carcinoma; and neuroblastoma. Orthologous to human ARID1B (AT-rich interaction domain 1B). [provided by Alliance of Genome Resources, Apr 2022]

Arid1b 基因产物(1)

mRNA Protein Name
NM_001085355.1 NP_001078824.1 AT-rich interactive domain-containing protein 1B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23540691 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within dendritic cell dendrite assembly IMP
IMP: 通过突变表型推断
26937011 MGI
acts upstream of or within dendritic spine development IMP
IMP: 通过突变表型推断
26937011 MGI
acts upstream of or within neuron-neuron synaptic transmission IMP
IMP: 通过突变表型推断
26937011 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SWI/SNF superfamily-type complex IDA
IDA: 通过直接分析推断
24335282 MGI
part of nBAF complex IDA
IDA: 通过直接分析推断
23785148 MGI
located in nucleus IDA
IDA: 通过直接分析推断
26937011 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

AT-rich interactive domain-containing protein 1B

ARID domain-containing protein 1B

AT rich interactive domain 1B (Swi1 like)

BRG1-associated factor 250b

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arid1b NCBI NCBI:57492