Arid1b - AT rich interactive domain 1B (SWI-like) Gene

种属: Mus musculus

同用名: Ardi1b; BAF250B; mKIAA1235; 8030481M12; 9330189K18Rik; B230217J03Rik

关于 Arid1b

功能概要

Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Acts upstream of or within dendritic cell dendrite assembly; dendritic spine development; and neuron-neuron synaptic transmission. Located in nucleus. Part of nBAF complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Coffin-Siris syndrome 1 and autism spectrum disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome; Coffin-Siris syndrome 1; intellectual disability; lung non-small cell carcinoma; and neuroblastoma. Orthologous to human ARID1B (AT-rich interaction domain 1B). [provided by Alliance of Genome Resources, Apr 2022]