2. Gene
  3. Spry1 - sprouty RTK signaling antagonist 1 Gene

Spry1 - sprouty RTK signaling antagonist 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: spry-1; sprouty1

基因 ID: 24063 | 基因类型: protein coding

关于 Spry1

功能概要

Involved in negative regulation of cell differentiation and negative regulation of signal transduction. Acts upstream of or within several processes, including bud elongation involved in lung branching; kidney development; and negative regulation of signal transduction. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; branchial arch; embryo ectoderm; limb; and sensory organ. Orthologous to human SPRY1 (sprouty RTK signaling antagonist 1). [provided by Alliance of Genome Resources, Apr 2022]

Spry1 基因产物(4)

mRNA Protein Name
NM_001305440.1 NP_001292369.1 protein sprouty homolog 1
NM_001305441.1 NP_001292370.1 protein sprouty homolog 1
NM_001305442.1 NP_001292371.1 protein sprouty homolog 1
NM_011896.3 NP_036026.1 protein sprouty homolog 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16339969 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of ERK1 and ERK2 cascade IGI
IGI: 通过遗传相互作用推断
21764747 MGI
acts upstream of or within bud elongation involved in lung branching IGI
IGI: 通过遗传相互作用推断
21764747 MGI
acts upstream of or within establishment of mitotic spindle orientation IGI
IGI: 通过遗传相互作用推断
21764747 MGI
acts upstream of or within metanephros development IGI
IGI: 通过遗传相互作用推断
17537792 MGI
acts upstream of or within negative regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
11585837 MGI
involved in negative regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
29501879 MGI
acts upstream of or within negative regulation of ERK1 and ERK2 cascade IGI
IGI: 通过遗传相互作用推断
21764747 MGI
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
19043405 MGI
acts upstream of or within negative regulation of GTPase activity IDA
IDA: 通过直接分析推断
11585837 MGI
acts upstream of or within negative regulation of MAP kinase activity IDA
IDA: 通过直接分析推断
16339969 MGI
acts upstream of or within negative regulation of Ras protein signal transduction IDA
IDA: 通过直接分析推断
11585837 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11585837 MGI
involved in negative regulation of epithelial to mesenchymal transition IDA
IDA: 通过直接分析推断
25576668 MGI
acts upstream of or within negative regulation of fibroblast growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
11585837 MGI
involved in negative regulation of lens fiber cell differentiation IDA
IDA: 通过直接分析推断
29501879 MGI
acts upstream of or within negative regulation of neurotrophin TRK receptor signaling pathway IDA
IDA: 通过直接分析推断
11585837 MGI
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
25576668 MGI
acts upstream of or within organ induction IMP
IMP: 通过突变表型推断
15691764 MGI
acts upstream of or within ureteric bud development IGI
IGI: 通过遗传相互作用推断
15691764 MGI
acts upstream of or within ureteric bud development IMP
IMP: 通过突变表型推断
15691764 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein sprouty homolog 1

inhibitor of receptor tyrosine kinases

sprouty homolog 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13721 SPRY1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21767 Spry1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28284 Spry1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spry1 NCBI NCBI:10252
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