1. Gene
  2. Spry4 - sprouty RTK signaling antagonist 4 Gene

Spry4 - sprouty RTK signaling antagonist 4 Gene

种属: Mus musculus

同用名: sprouty4; A030006O18Rik

基因 ID: 24066 | 基因类型: protein coding

关于 Spry4

功能概要

Predicted to enable protein kinase inhibitor activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and negative regulation of MAP kinase activity. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; germ layer; and nervous system. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 17 with or without anosmia. Orthologous to human SPRY4 (sprouty RTK signaling antagonist 4). [provided by Alliance of Genome Resources, Apr 2022]

Spry4 基因产物(1)

mRNA Protein Name
NM_011898.3 NP_036028.2 protein sprouty homolog 4
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16339969 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within negative regulation of MAP kinase activity IDA
IDA: 通过直接分析推断
16339969 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein sprouty homolog 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spry4 NCBI NCBI:81848