2. Gene
  3. Gad1 - glutamate decarboxylase 1 Gene

Gad1 - glutamate decarboxylase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Gad67

基因 ID: 24379 | 基因类型: protein coding

关于 Gad1

功能概要

Enables anion binding activity; glutamate decarboxylase activity; and protein N-terminus binding activity. Involved in gamma-aminobutyric acid biosynthetic process and response to xenobiotic stimulus. Located in presynaptic active zone. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in anxiety disorder; bipolar disorder; developmental and epileptic encephalopathy 89; and schizophrenia. Orthologous to human GAD1 (glutamate decarboxylase 1). [provided by Alliance of Genome Resources, Apr 2022]

Gad1 基因产物(1)

mRNA Protein Name
NM_017007.2 NP_058703.1 glutamate decarboxylase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glutamate binding IDA
IDA: 通过直接分析推断
10812196 RGD
enables glutamate decarboxylase activity IDA
IDA: 通过直接分析推断
1924335 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
7836456 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
7836456 RGD
enables pyridoxal phosphate binding IDA
IDA: 通过直接分析推断
1880546 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
11259512 RGD
involved in cellular response to serotonin IEP
IEP: 通过表达模式推断
20881131 RGD
involved in gamma-aminobutyric acid biosynthetic process IDA
IDA: 通过直接分析推断
1924335 RGD
involved in positive regulation of locomotion involved in locomotory behavior IMP
IMP: 通过突变表型推断
33293518 RGD
involved in response to auditory stimulus IEP
IEP: 通过表达模式推断
22428005 RGD
involved in response to caloric restriction IEP
IEP: 通过表达模式推断
15211593 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
19855903 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
15729141 RGD
involved in response to isolation stress IEP
IEP: 通过表达模式推断
22356888 RGD
involved in response to methamphetamine hydrochloride IEP
IEP: 通过表达模式推断
30275762 RGD
involved in response to morphine IEP
IEP: 通过表达模式推断
15673448 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
19855903 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
23932495 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19359144 RGD
involved in social behavior IMP
IMP: 通过突变表型推断
33293518 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuronal cell body IDA
IDA: 通过直接分析推断
20659561 RGD
located in presynaptic active zone IDA
IDA: 通过直接分析推断
24613359 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glutamate decarboxylase 1

67 kDa glutamic acid decarboxylase

GAD-67

Glutamate decarboxylase 1 (brain)

glutamate decarboxylase 1 variant GAD67NT

glutamic acid decarboxylase 1

相关产品

Approval
生物活性分子 (4)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0161A Duloxetine hydrochloride Inhibitor 99.97% 是
HY-B0161 Duloxetine Inhibitor 99.92% 是
HY-118901 Opipramol Antagonist 99.91% 否
HY-B0161AR Duloxetine hydrochloride (Standard) Inhibitor / 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-122487 Troriluzole Modulator 99.71% Phase 3
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-118901A Opipramol dihydrochloride Antagonist / 否
HY-122487A Troriluzole hydrochloride Modulator / 否
HY-B0161AS Duloxetine-d3 hydrochloride Inhibitor / 否
HY-B0161AS1 Duloxetine-d7 hydrochloride Inhibitor / 否
HY-RS05227 GAD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-B0161S Duloxetine-d7 Inhibitor / 否
HY-B0161S3 Duloxetine-d5 oxalate Inhibitor / 否
HY-RS17368 Gad1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23822 Gad1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gad1 NCBI NCBI:2571
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