2. Gene
  3. Ifnb1 - interferon beta 1 Gene

Ifnb1 - interferon beta 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ifnb; If1da1

基因 ID: 24481 | 基因类型: protein coding

关于 Ifnb1

功能概要

Predicted to enable chloramphenicol O-acetyltransferase activity; cytokine activity; and type I interferon receptor binding activity. Involved in macrophage activation involved in immune response. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFNB1 (interferon beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Ifnb1 基因产物(1)

mRNA Protein Name
NM_019127.2 NP_062000.1 interferon beta precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to dsDNA IEP
IEP: 通过表达模式推断
33115500 RGD
involved in cellular response to dsRNA IEP
IEP: 通过表达模式推断
15661832 RGD
involved in cellular response to exogenous dsRNA IEP
IEP: 通过表达模式推断
18223009 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18412159 RGD
involved in cellular response to virus IEP
IEP: 通过表达模式推断
15661832 RGD
involved in endoplasmic reticulum unfolded protein response IEP
IEP: 通过表达模式推断
18412159 RGD
involved in macrophage activation involved in immune response IDA
IDA: 通过直接分析推断
10496312 RGD
involved in negative regulation of blood-brain barrier permeability IDA
IDA: 通过直接分析推断
12973019 RGD
involved in negative regulation of cell adhesion molecule production IDA
IDA: 通过直接分析推断
12044977 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
9126338 RGD
involved in negative regulation of immunoglobulin production IDA
IDA: 通过直接分析推断
10494101 RGD
involved in negative regulation of matrix metallopeptidase secretion IDA
IDA: 通过直接分析推断
15222694 RGD
involved in negative regulation of mononuclear cell migration IDA
IDA: 通过直接分析推断
12044977 RGD
involved in negative regulation of neuroinflammatory response IDA
IDA: 通过直接分析推断
12973019 RGD
involved in negative regulation of type II interferon production IDA
IDA: 通过直接分析推断
10494101 RGD
involved in positive regulation of transforming growth factor beta production IDA
IDA: 通过直接分析推断
10494101 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interferon beta

IFN-beta

interferon 1da1

interferon beta 1, fibroblast

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990036 Dazukibart Inhibitor 99.76% Phase 3
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-138682 STING-IN-2 Inhibitor 99.71% 否
HY-RS06585 IFNB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17301 Ifnb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23756 Ifnb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ifnb1 NCBI NCBI:3456
Mus musculus Ifnb1 NCBI NCBI:15977
Macaca mulatta Ifnb1 NCBI NCBI:711414
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