2. Gene
  3. Klk1 - kallikrein 1 Gene

Klk1 - kallikrein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Kal; KALA; Klk5; Klk7; Klk1l; Klna3; RGK-7; Klk1c7; RSKG-7; RATKALA

基因 ID: 24523 | 基因类型: protein coding

关于 Klk1

功能概要

Enables endopeptidase activity. Involved in several processes, including positive regulation of acute inflammatory response; positive regulation of apoptotic process; and response to nutrient. Located in acrosomal vesicle; apical part of cell; and nucleus. Biomarker of hypertension and pancreatitis. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to human KLK1 (Kallikrein 1). [provided by Alliance of Genome Resources, Apr 2022]

Klk1 基因产物(1)

mRNA Protein Name
NM_012593.2 NP_036725.2 kallikrein 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables endopeptidase activity IDA
IDA: 通过直接分析推断
16231010 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of acute inflammatory response IMP
IMP: 通过突变表型推断
17015177 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
17015177 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17473535 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
12489811 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
12558526 RGD
located in apical part of cell IDA
IDA: 通过直接分析推断
12558526 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kallikrein 1

Kallikrein 1, renal/pancreas/salivary

esterase B

glandular kallikrein-7, submandibular/renal

kallikrein 1-like peptidase

kallikrein 1-related peptidase C7

kallikrein 5

kallikrein 7

kallikrein a3

kallikrein-related protein K1

proteinase A

renal k

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148949A Kallikrein 5-IN-2 TFA Inhibitor 99.53% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Klk1 NCBI NCBI:3816
Mus musculus Klk1 NCBI NCBI:16612
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z