2. Gene
  3. Chrna3 - cholinergic receptor nicotinic alpha 3 subunit Gene

Chrna3 - cholinergic receptor nicotinic alpha 3 subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25101 | 基因类型: protein coding

关于 Chrna3

功能概要

Enables acetylcholine binding activity; heterocyclic compound binding activity; and postsynaptic neurotransmitter receptor activity. Involved in several processes, including acetylcholine receptor signaling pathway; regulation of synaptic vesicle exocytosis; and response to nicotine. Located in several cellular components, including neuronal cell body; plasma membrane raft; and postsynaptic density. Part of acetylcholine-gated channel complex. Is active in cholinergic synapse and dopaminergic synapse. Is integral component of postsynaptic specialization membrane. Used to study visual epilepsy. Human ortholog(s) of this gene implicated in lung Cancer. Orthologous to human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna3 基因产物(1)

mRNA Protein Name
NM_052805.3 NP_434692.2 neuronal acetylcholine receptor subunit alpha-3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables acetylcholine binding IDA
IDA: 通过直接分析推断
11297818 RGD
enables acetylcholine receptor activity IDA
IDA: 通过直接分析推断
2444984 RGD
enables acetylcholine-gated monoatomic cation-selective channel activity IGI
IGI: 通过遗传相互作用推断
21540349 RGD
enables acetylcholine-gated monoatomic cation-selective channel activity IMP
IMP: 通过突变表型推断
11297818 RGD
enables heterocyclic compound binding IDA
IDA: 通过直接分析推断
15016836 RGD
enables heterocyclic compound binding IPI
IPI: 通过物理相互作用推断
15016836 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
20796176 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acetylcholine receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
21540349 RGD
involved in heart development IEP
IEP: 通过表达模式推断
15549397 RGD
involved in presynaptic modulation of chemical synaptic transmission EXP
EXP: 通过实验结果推断
12065717 RGD
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
12065717 RGD
involved in response to acetylcholine IGI
IGI: 通过遗传相互作用推断
21540349 RGD
involved in response to carbon monoxide IEP
IEP: 通过表达模式推断
24704181 RGD
involved in response to nicotine IEP
IEP: 通过表达模式推断
17105949 RGD
involved in response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
15896488 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of acetylcholine-gated channel complex IDA
IDA: 通过直接分析推断
20796176 RGD
part of acetylcholine-gated channel complex IGI
IGI: 通过遗传相互作用推断
21540349 RGD
is active in cholinergic synapse IDA
IDA: 通过直接分析推断
3380297 RGD
located in dendrite IDA
IDA: 通过直接分析推断
11297818 RGD
is active in dopaminergic synapse EXP
EXP: 通过实验结果推断
12065717 RGD
is active in dopaminergic synapse IDA
IDA: 通过直接分析推断
12065717 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
11297818 RGD
located in plasma membrane raft IGI
IGI: 通过遗传相互作用推断
21540349 RGD
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
3380297 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
16129735 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuronal acetylcholine receptor subunit alpha-3

Acetylcholine receptor alpha 3 (neuronal nicotine)

acetylcholine receptor alpha3

cetylcholine receptor alpha 3 (neuronal nicotine)

cholinergic receptor nicotinic alpha polypeptide 4

cholinergic receptor, nicotinic, alpha 3 (neuronal)

cholinergic rece

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02668 CHRNA3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20143 Chrna3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26647 Chrna3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrna3 NCBI NCBI:1136
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