1. Gene
  2. Aqp1 - aquaporin 1 Gene

Aqp1 - aquaporin 1 Gene

种属: Rattus norvegicus

同用名: CHIP28

基因 ID: 25240 | 基因类型: protein coding

关于 Aqp1

功能概要

Enables glycerol transmembrane transporter activity and water channel activity. Involved in several processes, including glycerol transport; lateral ventricle development; and positive regulation of lamellipodium assembly. Located in several cellular components, including basolateral plasma membrane; brush border; and neuronal cell body membrane. Biomarker of artery disease (multiple); autosomal recessive polycystic kidney disease; brain disease (multiple); diabetes mellitus; and uveitis. Orthologous to human AQP1 (Aquaporin 1 (Colton blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Aqp1 基因产物(1)

mRNA Protein Name
NM_012778.2 NP_036910.1 aquaporin-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glycerol transmembrane transporter activity IDA
IDA: 通过直接分析推断
7491270 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16354160 RGD
enables water channel activity IMP
IMP: 通过突变表型推断
11804854 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glycerol transmembrane transport IDA
IDA: 通过直接分析推断
7491270 RGD
involved in hyperosmotic response IEP
IEP: 通过表达模式推断
19776169 RGD
involved in lateral ventricle development IEP
IEP: 通过表达模式推断
16133142 RGD
involved in metanephric proximal tubule development IEP
IEP: 通过表达模式推断
30645697 RGD
involved in positive regulation of epithelial cell migration IMP
IMP: 通过突变表型推断
19539607 RGD
involved in positive regulation of lamellipodium assembly IMP
IMP: 通过突变表型推断
19539607 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
19351613 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
18248364 RGD
involved in water transport IMP
IMP: 通过突变表型推断
11804854 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
16133142 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
17553469 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
11804854 RGD
located in brush border IDA
IDA: 通过直接分析推断
16133142 RGD
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
16309835 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
7491270 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

aquaporin-1

AQP-1

Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP))

aquaporin 1 (Colton blood group)

aquaporin-CHIP

water channel protein for red blood cells and kidney proximal tubule

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aqp1 NCBI NCBI:358