1. Gene
  2. Cd74 - CD74 molecule Gene

Cd74 - CD74 molecule Gene

种属: Rattus norvegicus

同用名: INVG34

基因 ID: 25599 | 基因类型: protein coding

关于 Cd74

功能概要

Predicted to enable several functions, including amyloid-beta binding activity; macrophage migration inhibitory factor binding activity; and signaling receptor binding activity. Predicted to contribute to cytokine binding activity. Involved in cell population proliferation and positive regulation of MAPK cascade. Predicted to be located in several cellular components, including Golgi apparatus; external side of plasma membrane; and multivesicular body. Predicted to be integral component of membrane. Predicted to be part of MHC class II protein complex; NOS2-CD74 complex; and macrophage migration inhibitory factor receptor complex. Predicted to be active in cell surface and cytoplasm. Orthologous to human CD74 (CD74 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd74 基因产物(1)

mRNA Protein Name
NM_013069.2 NP_037201.1 H-2 class II histocompatibility antigen gamma chain
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
12782713 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

H-2 class II histocompatibility antigen gamma chain

Cd74 molecule, major histocompatibility complex, class II invariant chain

MHC class II-associated invariant chain

ia antigen-associated invariant chain

ii

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd74 NCBI NCBI:972
Mus musculus Cd74 NCBI NCBI:16149