1. Gene
  2. MTG2 - mitochondrial ribosome associated GTPase 2 Gene

MTG2 - mitochondrial ribosome associated GTPase 2 Gene

中文名称:线粒体核糖体相关 GTPase 2

种属: Homo sapiens

同用名: ObgH1; GTPBP5; dJ1005F21.2

基因 ID: 26164 | 基因类型: protein coding

关于 MTG2

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:62,183,028-62,203,568 (from NCBI)

This gene has 10 transcripts (splice variants), 203 orthologues and 4 paralogues. Ubiquitous expression in testis (RPKM 3.6), skin (RPKM 3.3) and 25 other tissues.

功能概要

小 G 蛋白,如 GTPBP5,充当分子开关,在调节蛋白质合成、核转运、膜运输和信号转导等基本细胞过程中起着至关重要的作用 (Hirano 等人,2006 [PubMed 17054726]) 。[OMIM 提供,2008 年 3 月]

Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008]

MTG2 基因产物(3)

mRNA Protein Name
NM_001384347.1 NP_001371276.1 mitochondrial ribosome-associated GTPase 2 isoform 1
NM_001384348.1 NP_001371277.1 mitochondrial ribosome-associated GTPase 2 isoform 3
NM_015666.4 NP_056481.1 mitochondrial ribosome-associated GTPase 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activity IDA
IDA: 通过直接分析推断
23396448 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of mitochondrial translation IMP
IMP: 通过突变表型推断
23396448 GOA
involved in regulation of respiratory system process IMP
IMP: 通过突变表型推断
23396448 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
23396448 GOA
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
23396448 GOA
located in mitochondrial ribosome IDA
IDA: 通过直接分析推断
23396448 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MTG2 蛋白结构

GTP1_OBG

GTP1_OBG: GTP1/OBG (72 - 223)

MMR_HSR1

MMR_HSR1: 50S ribosome-binding GTPase (227 - 346)

  • 0
  • 100
  • 200
  • 300
  • 406 a.a.
蛋白主名 其他名称

mitochondrial ribosome-associated GTPase 2

GTP binding protein 5 (putative)

关联疾病

疾病名称 别名
Endocervicitis
Bone Osteosarcoma

Osteosarcoma Of Bone

Primary Osteosarcoma Of Bone

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus MTG2 MGD MGI:106565
Bos taurus MTG2 VGNC VGNC:31729
Rattus norvegicus MTG2 RGD RGD:1359243
Canis familiaris MTG2 VGNC VGNC:43471
Macaca mulatta MTG2 VGNC VGNC:74972
Felis catus MTG2 VGNC VGNC:63649