2. Gene
  3. Ccnb1 - cyclin B1 Gene

Ccnb1 - cyclin B1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CycB1; Cycb-4; Cycb-5; Ccnb1-rs1; Cycb1-rs1; Ccnb1-rs13

基因 ID: 268697 | 基因类型: protein coding

关于 Ccnb1

功能概要

Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; enzyme binding activity; and patched binding activity. Acts upstream of or within several processes, including histone H3-S10 phosphorylation involved in chromosome condensation; in utero embryonic development; and positive regulation of fibroblast proliferation. Located in cytoplasm; membrane; and nucleus. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in breast Cancer and prostate Cancer. Orthologous to human CCNB1 (cyclin B1). [provided by Alliance of Genome Resources, Apr 2022]

Ccnb1 基因产物(1)

mRNA Protein Name
NM_172301.3 NP_758505.2 G2/mitotic-specific cyclin-B1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12124778 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
9539739 MGI
acts upstream of or within positive regulation of cell cycle IDA
IDA: 通过直接分析推断
22053081 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: 通过突变表型推断
22053081 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
12124778 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
17325031 MGI
located in membrane IDA
IDA: 通过直接分析推断
9539739 MGI
colocalizes with mitochondrial matrix IDA
IDA: 通过直接分析推断
24746669 MGI
located in nucleus IDA
IDA: 通过直接分析推断
14993286 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

G2/mitotic-specific cyclin-B1

cyclin B1, related sequence 1

cyclin B1, related sequence 13

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114779 N9-Isopropylolomoucine Inhibitor 99.34% 否
HY-RS02118 CCNB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-162895 NL13 / 否
HY-RS02119 CCNB1IP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17545 Ccnb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24004 Ccnb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccnb1 NCBI NCBI:891
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