1. Gene
  2. GOLIM4 - golgi integral membrane protein 4 Gene

GOLIM4 - golgi integral membrane protein 4 Gene

中文名称:高尔基整合膜蛋白 4

种属: Homo sapiens

同用名: P138; GIMPC; GOLPH4; GPP130

基因 ID: 27333 | 基因类型: protein coding

关于 GOLIM4

Cytogenetic location: 3q26.2 Genomic coordinates (GRCh38): 3:168,008,689-168,095,924 (from NCBI)

This gene has 3 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in small intestine (RPKM 37.0), colon (RPKM 33.7) and 24 other tissues.

功能概要

高尔基复合体在内质网输出的蛋白质的分类和修饰中起着关键作用。该基因编码的蛋白质是 II 型高尔基体常驻蛋白。它可以处理在粗面内质网中合成的蛋白质,并协助通过高尔基体运输蛋白质货物。[RefSeq 提供,2008 年 7 月]

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi-resident protein. It may process proteins synthesized in the rough endoplasmic reticulum and assist in the transport of protein cargo through the Golgi apparatus. [provided by RefSeq, Jul 2008]

GOLIM4 基因产物(2)

mRNA Protein Name
NM_001308155.2 NP_001295084.1 Golgi integral membrane protein 4 isoform 2
NM_014498.5 NP_055313.1 Golgi integral membrane protein 4 isoform 1
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
9201717 GOA
located in membrane IDA
IDA: 通过直接分析推断
9201717 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

Golgi integral membrane protein 4

130 kDa golgi-localized phosphoprotein

GOLIM4 抗体

目录号 产品名 应用 反应物种
HY-P82494 GOLPH4 Antibody (YA2239) WB, IHC-P Human

关联疾病

疾病名称 别名
Congenital Disorder Of Glycosylation, Type Iig

CDG2G

Congenital Disorder Of Glycosylation Type Iig

Cdg Iig

Cdgiig

Cdgii/Cog1 Cerebrocostomandibular-Like Syndrome

Carbohydrate Deficient Glycoprotein Syndrome Type Iig

Cdg-Iig

Congenital Disorder Of Glycosylation, Type 2g

Cog1-Cdg

Cdg Syndrome Type Iig

Congenital Disorder Of Glycosylation Type 2g

Congenital Disorder Of Glycosylation 2g

Cdg-Ii Caused By Cog1 Deficiency

Glycosylation, Congenital Disorder Of, Type Iig

Spinal Muscular Atrophy, Distal, Autosomal Recessive, 3

Distal Spinal Muscular Atrophy Type 3

DSMA3

Spinal Muscular Atrophy, Chronic Distal, Autosomal Recessive

Autosomal Recessive Distal Spinal Muscular Atrophy Type 3

Dhmn3 And Dhmn4

Distal Hereditary Motor Neuropathy Type 3 And Type 4

Neuronopathy, Distal Hereditary Motor, Type Iv

Hmn4

Dhmn4

Neuropathy, Distal Hereditary Motor, Type Iv

Hmn Iv

Neuronopathy, Distal Hereditary Motor, Type Iii

Hmn3

Dhmn3

Hmn Iii

Phosphoglycerate Dehydrogenase Deficiency

Phgdh Deficiency

3-Phosphoglycerate Dehydrogenase Deficiency

PHGDHD

3-Pgdh Deficiency

3-Phosphoglycerate Dehydrogenase Deficiency, Infantile/Juvenile Form

Phgdh Deficiency, Infantile/Juvenile Form

Deficiency, Phosphoglycerate Dehydrogenase

Congenital Disorder Of Glycosylation, Type In

Congenital Disorder Of Glycosylation

CDG1N

Congenital Disorders Of Glycosylation

Cdg In

Cdgin

Congenital Disorder Of Glycosylation 1n

Carbohydrate-Deficient Glycoprotein Syndrome

Cdg

Rft1-Cdg

Cdg-In

Congenital Disorder Of Glycosylation Type In

Carbohydrate Deficient Glycoprotein Syndrome

Cdg Syndrome

Congenital Disorder Of Glycosylation In

Carbohydrate-Deficient Glycoprotein Syndromes

Cdg Syndrome Type In

Carbohydrate Deficient Glycoprotein Syndrome Type In

Congenital Disorder Of Glycosylation Type 1n

Man5glcnac2-Pp-Dol Flippase Deficiency

Glycosylation, Congenital Disorder Of

Glycosylation, Congenital Disorder Of, Type In

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus GOLIM4 VGNC VGNC:29490
Rattus norvegicus GOLIM4 RGD RGD:1310948
Felis catus GOLIM4 VGNC VGNC:62642
Mus musculus GOLIM4 MGD MGI:1920374
Canis familiaris GOLIM4 VGNC VGNC:41344
Macaca mulatta GOLIM4 VGNC VGNC:72945