NPW - neuropeptide W Gene

中文名称：神经肽 W

种属: Homo sapiens

同用名: L8; L8C; PPL8; PPNPW

关于 NPW

功能概要

该基因的产物被加工成 23 个和 30 个氨基酸的神经肽，它们结合并激活中枢神经系统中的两个 G 蛋白偶联受体。神经肽已被证明可通过腺苷酸环化酶/蛋白激酶 A 信号级联增强肾上腺细胞皮质醇的分泌。使用非 AUG 起始密码子翻译前原蛋白，该密码子是从小鼠直系同源物的分析中推断出来的。[RefSeq 提供，2008 年 7 月]

The product of this gene is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the Adenylate Cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq, Jul 2008]