1. Gene
  2. Spint2 - serine peptidase inhibitor, Kunitz type, 2 Gene

Spint2 - serine peptidase inhibitor, Kunitz type, 2 Gene

种属: Rattus norvegicus

同用名: Pb; HAI-2

基因 ID: 292770 | 基因类型: protein coding

关于 Spint2

功能概要

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in cellular response to BMP stimulus and negative regulation of neural precursor cell proliferation. Located in plasma membrane. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 3. Orthologous to human SPINT2 (serine peptidase inhibitor, Kunitz type 2). [provided by Alliance of Genome Resources, Apr 2022]

Spint2 基因产物(2)

mRNA Protein Name
NM_001082549.1 NP_001076018.1 kunitz-type protease inhibitor 2 isoform a precursor
NM_199087.1 NP_954518.1 kunitz-type protease inhibitor 2 isoform b precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to BMP stimulus IEP
IEP: 通过表达模式推断
23409135 RGD
involved in negative regulation of neural precursor cell proliferation IMP
IMP: 通过突变表型推断
23409135 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

kunitz-type protease inhibitor 2

hepatocyte growth factor activator inhibitor type 2

placental bikunin

serine protease inhibitor, Kunitz type 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spint2 NCBI NCBI:10653
Mus musculus Spint2 NCBI NCBI:20733