1. Gene
  2. Cln3 - CLN3 lysosomal/endosomal transmembrane protein, battenin Gene

Cln3 - CLN3 lysosomal/endosomal transmembrane protein, battenin Gene

种属: Rattus norvegicus

基因 ID: 293485 | 基因类型: protein coding

关于 Cln3

功能概要

Predicted to enable calcium-dependent protein binding activity and sulfatide binding activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; regulation of vesicle-mediated transport; and vacuole organization. Predicted to act upstream of or within several processes, including autophagosome maturation; regulation of cellular protein metabolic process; and regulation of filopodium assembly. Located in plasma membrane. Colocalizes with Golgi apparatus and endosome. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 3. Orthologous to human CLN3 (CLN3 lysosomal/endosomal transmembrane protein, battenin). [provided by Alliance of Genome Resources, Apr 2022]

Cln3 基因产物(1)

mRNA Protein Name
NM_001006971.1 NP_001006972.1 battenin
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
15240864 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

battenin

CLN3, battenin

Cln3p

ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)

ceroid-lipofuscinosis, neuronal 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cln3 NCBI NCBI:1201