HOXD1 - homeobox D1 Gene

中文名称：同源框 D1

种属: Homo sapiens

同用名: HOX4; HOX4G; Hox-4.7

关于 HOXD1

功能概要

该基因是 Antp 同源框家族的成员，编码具有同源框 DNA 结合域的蛋白质。这种核蛋白作为参与分化和肢体发育的序列特异性转录因子发挥作用。该基因的突变与前后 (ap) 肢体轴上的严重发育缺陷有关。[RefSeq 提供，2008 年 7 月]

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008]