1. Gene
  2. Tbx3 - T-box transcription factor 3 Gene

Tbx3 - T-box transcription factor 3 Gene

种属: Rattus norvegicus

基因 ID: 353305 | 基因类型: protein coding

关于 Tbx3

功能概要

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of apoptotic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in ulnar-mammary syndrome. Orthologous to human TBX3 (T-box transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Tbx3 基因产物(1)

mRNA Protein Name
NM_181638.2 NP_853669.1 T-box transcription factor TBX3
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
15694670 RGD
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18285513 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

T-box transcription factor TBX3

T-box 3 (ulnar mammary syndrome)

T-box protein 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tbx3 NCBI NCBI:6926