1. Gene
  2. Tial1 - Tia1 cytotoxic granule-associated RNA binding protein-like 1 Gene

Tial1 - Tia1 cytotoxic granule-associated RNA binding protein-like 1 Gene

种属: Rattus norvegicus

基因 ID: 361655 | 基因类型: protein coding

关于 Tial1

功能概要

Predicted to enable mRNA 3'-UTR AU-rich region binding activity and mRNA binding activity involved in posttranscriptional gene silencing. Predicted to be involved in negative regulation of cell population proliferation; positive regulation of gene silencing by miRNA; and positive regulation of hippo signaling. Predicted to act upstream of or within germ cell development; positive regulation of cell population proliferation; and stem cell division. Located in cytoplasmic stress granule and nucleus. Part of ribonucleoprotein complex. Biomarker of transient cerebral ischemia. Orthologous to human TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1). [provided by Alliance of Genome Resources, Apr 2022]

Tial1 基因产物(1)

mRNA Protein Name
NM_001013193.1 NP_001013211.1 nucleolysin TIAR
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
22555848 RGD
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
12855701 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

nucleolysin TIAR

RNA binding protein TIAR (TIA-1 related)

Tial 1 cytotoxic granule-associated RNA- binding protein-like 1

Tial1 cytotoxic granule-associated RNA binding protein-like 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tial1 NCBI NCBI:7073