2. Gene
  3. MTCP1 - mature T cell proliferation 1 Gene

MTCP1 - mature T cell proliferation 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：成熟 T 细胞增殖 1

种属: Homo sapiens

同用名: TCL1C; p8MTCP1; P13MTCP1

基因 ID: 4515 | 基因类型: protein coding

关于 MTCP1

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:155,064,034-155,071,136 (from NCBI)

This gene has 4 transcripts (splice variants), 117 orthologues, 2 paralogues and is associated with 57 phenotypes. Ubiquitous expression in testis (RPKM 2.8), heart (RPKM 2.6) and 25 other tissues.

功能概要

该基因是通过参与一些与成熟 T 细胞增殖相关的 t (X;14) 易位来鉴定的。这个区域有一个复杂的基因结构，有一个共同的启动子和 5' 外显子剪接成两组不同的 3' 外显子，编码两种不同的蛋白质。该基因代表 TCL1 家族成员的上游 13 kDa 蛋白。这种蛋白质可能参与白血病发生。[RefSeq 提供，2009 年 3 月]

This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the upstream 13 kDa protein that is a member of the TCL1 family. This protein may be involved in leukemogenesis. [provided by RefSeq, Mar 2009]

MTCP1 基因产物(1)

mRNA Protein Name
NM_001018025.4 NP_001018025.1 protein p13 MTCP-1

MTCP1 蛋白结构

TCL1_MTCP1

TCL1_MTCP1: TCL1/MTCP1 family (3 - 105)

  • 0
  • 100
  • 107 a.a.
蛋白主名 其他名称

protein p13 MTCP-1

MTCP-1 type B1

关联疾病

疾病名称 别名
Prolymphocytic Leukemia

Pll

Prolymphocytic Leukaemia

Leukemia Prolymphocytic

Leukemia, Prolymphocytic
T-Cell Prolymphocytic Leukemia

T Cell Prolymphocytic Leukemia

Prolymphocytic Leukemia, T-Cell Type

T-Pll

T-Cell Chronic Lymphocytic Leukemia

Lymphocytic Leukemia T-Cell Chronic

Doid:0081042

Leukemia, T-Cell, Chronic

Prolymphocytic Leukaemia Of T-Cell Type Without Mention Of Remission
Ataxia-Telangiectasia

Ataxia Telangiectasia

Louis-Bar Syndrome

AT

At1

Ataxia-Telangiectasia Syndrome

Ataxia - Telangiectasia Variant

Boder-Sedgwick Syndrome

Louis Bar Syndrome

Cerebello-Oculocutaneous Telangiectasia

Immunodeficiency With Ataxia Telangiectasia

A-T

Ataxia Telangiectasia Syndrome

Atm

Telangiectasia, Cerebello-Oculocutaneous

Ataxia-Telangiectasia Variant
Leukemia

Leukemias

Leukaemia, Unspecified, Without Mention Of Remission

Aleukemic Leukaemia

Chronic Leukaemia

Subacute Leukaemia

Leukaemia Disorder

Leukaemia Nos
Incontinentia Pigmenti

Bloch-Sulzberger Syndrome

IP

Incontinentia Pigmenti, Familial Male-Lethal Type

Incontinentia Pigmenti Syndrome

Bloch-Siemens Syndrome

Ip2

Incontinentia Pigmenti, Type Ii, Formerly

Ip2, Formerly

Incontinentia Pigmenti Type 2

Bloch-Siemens-Sulzberger Syndrome

Familial Incontinentia Pigmenti Male-Lethal Type

Familial Incontinentia Pigmenti Type Ii

Incontinentia Pigmenti, Type Ii

Bloch Sulzberger Syndrome

Incontinentia Pigmenti Achromians

Incontinentia Pigmenti Of Bloch-Sulzberger

Nevus Pigmentosus Systematicus
T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02858 CMC4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS08760 MTCP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12821 SH2D1A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MTCP1 RGD RGD:1561352
Bos taurus MTCP1 VGNC VGNC:50220
Canis familiaris MTCP1 VGNC VGNC:43461
Mus musculus MTCP1 MGD MGI:102699
Macaca mulatta MTCP1 VGNC VGNC:74945
Felis catus MTCP1 VGNC VGNC:68337
Others MTCP1 NCBI
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