Ucp2 - uncoupling protein 2 Gene

种属: Rattus norvegicus

关于 Ucp2

功能概要

Predicted to enable Oxidative Phosphorylation uncoupler activity. Involved in several processes, including cellular response to glucose stimulus; liver regeneration; and negative regulation of Insulin secretion involved in cellular response to glucose stimulus. Located in mitochondrion. Used to study hypertension; non-alcoholic fatty liver disease; transient cerebral ischemia; and type 2 diabetes mellitus. Biomarker of congestive heart failure; fatty liver disease (multiple); hypothyroidism; obstructive jaundice; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in carotid artery disease; diabetic neuropathy; end stage renal disease; hypertension; and obesity. Orthologous to human UCP2 (uncoupling protein 2). [provided by Alliance of Genome Resources, Apr 2022]