2. Gene
  3. P3h1 - prolyl 3-hydroxylase 1 Gene

P3h1 - prolyl 3-hydroxylase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gros1; Lepre1; 2410024C15Rik

基因 ID: 56401 | 基因类型: protein coding

关于 P3h1

功能概要

Predicted to enable procollagen-proline 3-dioxygenase activity. Acts upstream of or within Collagen fibril organization; negative regulation of cell growth; and regulation of ossification. Predicted to be located in basement membrane; cytoplasm; and nucleus. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; limb mesenchyme; sensory organ; and skeleton. Used to study osteogenesis imperfecta type 8. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 8. Orthologous to human P3H1 (prolyl 3-hydroxylase 1). [provided by Alliance of Genome Resources, Apr 2022]

P3h1 基因产物(4)

mRNA Protein Name
NM_001042411.1 NP_001035874.1 prolyl 3-hydroxylase 1 isoform 3
NM_001286148.1 NP_001273077.1 prolyl 3-hydroxylase 1 isoform 4 precursor
NM_019782.3 NP_062756.2 prolyl 3-hydroxylase 1 isoform 1 precursor
NM_019783.2 NP_062757.2 prolyl 3-hydroxylase 1 isoform 2 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within collagen fibril organization IMP
IMP: 通过突变表型推断
20363744 MGI
acts upstream of or within negative regulation of cell growth IDA
IDA: 通过直接分析推断
10951563 MGI
acts upstream of or within regulation of ossification IMP
IMP: 通过突变表型推断
20363744 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prolyl 3-hydroxylase 1

growth suppressor 1

leprecan 1

leucine- and proline-enriched proteoglycan 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16280 FAM-labeled P3H1 Human Pre-designed siRNA Set A / 否
HY-RS09938 P3H1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20791 P3h1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27305 P3h1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P3h1 NCBI NCBI:64175
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