2. Gene
  3. Clec7a - C-type lectin domain family 7, member a Gene

Clec7a - C-type lectin domain family 7, member a Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BGR; beta-GR; Clecsf12

基因 ID: 56644 | 基因类型: protein coding

关于 Clec7a

功能概要

Predicted to enable (1->3)-beta-D-glucan binding activity and pattern recognition receptor activity. Predicted to be involved in several processes, including phagocytosis, recognition; positive regulation of cytokine production involved in inflammatory response; and response to fungus. Predicted to be active in cell surface. Is expressed in brain; gut; limb; musculature; and ventral grey horn. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Orthologous to human CLEC7A (C-type lectin domain containing 7A). [provided by Alliance of Genome Resources, Apr 2022]

Clec7a 基因产物(2)

mRNA Protein Name
NM_001309637.2 NP_001296566.1 C-type lectin domain family 7 member A isoform 2
NM_020008.4 NP_064392.2 C-type lectin domain family 7 member A isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables (1->3)-beta-D-glucan binding IDA
IDA: 通过直接分析推断
12163569 MGI
enables (1->3)-beta-D-glucan immune receptor activity IDA
IDA: 通过直接分析推断
12719478 MGI
enables opsonin binding IDA
IDA: 通过直接分析推断
12163569 MGI
enables pattern recognition receptor activity IDA
IDA: 通过直接分析推断
19136564 MGI
enables pattern recognition receptor activity IMP
IMP: 通过突变表型推断
15213161 MGI
enables polysaccharide binding IDA
IDA: 通过直接分析推断
12163569 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15845454 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in antifungal innate immune response IDA
IDA: 通过直接分析推断
19136564 MGI
involved in antifungal innate immune response IMP
IMP: 通过突变表型推断
17159984 MGI
involved in cell activation IDA
IDA: 通过直接分析推断
19136564 MGI
acts upstream of or within cell surface pattern recognition receptor signaling pathway IDA
IDA: 通过直接分析推断
12719478 MGI
acts upstream of or within cell-cell adhesion IDA
IDA: 通过直接分析推断
14698225 MGI
involved in cellular response to molecule of fungal origin IDA
IDA: 通过直接分析推断
15845454 MGI
involved in detection of molecule of fungal origin IDA
IDA: 通过直接分析推断
15213161 MGI
acts upstream of or within detection of yeast IDA
IDA: 通过直接分析推断
14698225 MGI
involved in detection of yeast IDA
IDA: 通过直接分析推断
19136564 MGI
involved in innate immune response IDA
IDA: 通过直接分析推断
15845454 MGI
involved in leukocyte activation involved in immune response IDA
IDA: 通过直接分析推断
15845454 MGI
acts upstream of or within phagocytosis, engulfment IDA
IDA: 通过直接分析推断
14707091 MGI
acts upstream of or within phagocytosis, recognition IDA
IDA: 通过直接分析推断
14707091 MGI
acts upstream of or within positive regulation of DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
19136564 MGI
involved in positive regulation of NF-kappaB transcription factor activity IDA
IDA: 通过直接分析推断
19136564 MGI
involved in positive regulation of T-helper 17 type immune response IMP
IMP: 通过突变表型推断
32358020 MGI
acts upstream of positive regulation of calcium-mediated signaling IDA
IDA: 通过直接分析推断
19136564 MGI
involved in positive regulation of canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
15213161 MGI
involved in positive regulation of cytokine production involved in immune response IDA
IDA: 通过直接分析推断
27288407 MGI
involved in positive regulation of dendritic cell cytokine production IDA
IDA: 通过直接分析推断
27288407 MGI
involved in positive regulation of dendritic cell cytokine production IMP
IMP: 通过突变表型推断
19136564 MGI
involved in positive regulation of interleukin-10 production IMP
IMP: 通过突变表型推断
19136564 MGI
involved in positive regulation of interleukin-2 production IMP
IMP: 通过突变表型推断
19136564 MGI
involved in positive regulation of interleukin-23 production IMP
IMP: 通过突变表型推断
19136564 MGI
involved in positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
19136564 MGI
involved in positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
27288407 MGI
acts upstream of or within positive regulation of phagocytosis IDA
IDA: 通过直接分析推断
14707091 MGI
involved in positive regulation of stress-activated MAPK cascade IDA
IDA: 通过直接分析推断
27288407 MGI
acts upstream of or within positive regulation of tumor necrosis factor production IDA
IDA: 通过直接分析推断
12719478 MGI
involved in positive regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
19136564 MGI
acts upstream of or within regulation of calcineurin-NFAT signaling cascade IMP
IMP: 通过突变表型推断
19136564 MGI
involved in regulation of canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
19136564 MGI
acts upstream of or within response to molecule of fungal origin IDA
IDA: 通过直接分析推断
12719478 MGI
acts upstream of or within response to yeast IDA
IDA: 通过直接分析推断
12719478 MGI
involved in response to yeast IDA
IDA: 通过直接分析推断
19136564 MGI
involved in stimulatory C-type lectin receptor signaling pathway IDA
IDA: 通过直接分析推断
19136564 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
12163569 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-type lectin domain family 7 member A

C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12

C-type lectin superfamily member 12

DC-associated C-type lectin 1

beta-glucan receptor

dectin-1

dendritic cell-associated C-type lectin 1

重组 Clec7a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75296 Dectin-1/CLEC7A Protein, Mouse (HEK293, His, solution) NP_064392.2 (F69-L244) ≥95%
HY-P700694 Dectin-1/CLEC7A Protein, Mouse (HEK293, Fc) Q6QLQ4 (G71-L244) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-147295 Odetiglucan Agonist / Phase 1
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02800 CLEC7A Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS17778 Clec7a Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS24245 Clec7a Rat Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990374 Anti-CLEC7A Antibody Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Clec7a NCBI NCBI:64581
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z