1. Gene
  2. PSG4 - pregnancy specific beta-1-glycoprotein 4 Gene

PSG4 - pregnancy specific beta-1-glycoprotein 4 Gene

中文名称:妊娠特异性 β-1-糖蛋白 4

种属: Homo sapiens

同用名: PSG9; PSBG-4; PSBG-9

基因 ID: 5672 | 基因类型: protein coding

关于 PSG4

Cytogenetic location: 19q13.31 Genomic coordinates (GRCh38): 19:43,192,702-43,205,638 (from NCBI)

This gene has 17 transcripts (splice variants), 627 orthologues and 24 paralogues. Restricted expression toward placenta (RPKM 137.5).

功能概要

该基因编码的蛋白质是一种妊娠特异性糖蛋白 (PSG) ,是 19 号染色体上一组相似基因编码的几种蛋白质之一。该基因是癌胚抗原 (CEA) 基因家族的成员,可能在妊娠中发挥作用先天免疫系统的调节。已发现该基因编码不同亚型的几种转录变体。[RefSeq 提供,2015 年 10 月]

The protein encoded by this gene is a pregnancy-specific glycoprotein (PSG), one of several encoded by a cluster of similar genes on chromosome 19. This gene is a member of the carcinoembryonic antigen (CEA) gene family and may play a role in regulation of the innate immune system. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

PSG4 基因产物(4)

mRNA Protein Name
NM_001276495.2 NP_001263424.1 pregnancy-specific beta-1-glycoprotein 4 isoform 3 precursor
NM_001316339.2 NP_001303268.1 pregnancy-specific beta-1-glycoprotein 4 isoform 4
NM_002780.5 NP_002771.2 pregnancy-specific beta-1-glycoprotein 4 isoform 1 precursor
NM_213633.3 NP_998798.1 pregnancy-specific beta-1-glycoprotein 4 isoform 2 precursor

PSG4 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (37 - 127)

Ig_2

Ig_2: Immunoglobulin domain (148 - 234)

Ig_2

Ig_2: Immunoglobulin domain (251 - 328)

Ig_2

Ig_2: Immunoglobulin domain (335 - 413)

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  • 419 a.a.
蛋白主名 其他名称

pregnancy-specific beta-1-glycoprotein 4

PS-beta-G-4